Clinical Trials in Chicago

Showing 4401-4420 of 20,493 trials

Use of EndoFLIP and Manometry Prior to G-POEM

NCT04844190

The purpose of this study is to assess physiologic response of therapy in patients with refractory gastroparesis undergoing Gastric per-oral endoscopic myotomy (G-POEM) using endoscopic functional lumen imaging probe (EndoFLIP) and antroduodenal manometry (ADM). Refractory gastroparesis will be defined as having delayed gastric emptying at four hours (\>10% retention of stomach contents) on gastric scintigraphy and persistent symptoms despite treatment with dietary modification or prokinetic medications. We hypothesize that EndoFLIP and high resolution ADM will provide an individualized pyloric functional profile in gastroparesis patients that can more accurately predict clinical response to G-POEM.

Gastroparesis

Northwestern UniversityStarted Sep 2021

Chicago, Illinois, United States

Not Yet RecruitingEARLY Phase 12.2 miles

Research Investigating Drug Effects-2 (RiDE-2)

NCT06758596

The purpose of this study is to better understand how people's mood, behavior, and brains respond to different recreational drugs. We are also trying to understand why some people may feel differently or their brain may respond differently than other people after taking the same recreational drug.

Cannabis UseSubstance Use Disorder (SUD)Healthy

University of Illinois at Chicago144 participantsStarted Jul 2026

Chicago, Illinois, United States

Use of EndoFLIP and Manometry Prior to G-POEM

Research Investigating Drug Effects-2 (RiDE-2)

Find Trials by Condition in Chicago

A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors

A Study of Glutathione in Children With Autism Spectrum Disorder

Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

Clinical Effectiveness Assessment of VeriStrat® Testing and Validation of Immunotherapy Tests in NSCLC Subjects

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)

Multi-Site Feasibility Testing of the Ventricular Assist Device Anticipatory Guidance Tool

Ascending Dose Study of FrontlineODP™ Spray Dried Plasma

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules

Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)

Short-course Regimens for the Treatment of Pulmonary Tuberculosis

Post COVID-19 Condition

Health Care Workers Cohort Study in the EuCARE Project (EuCARE-HCW)