Clinical Trials in Chicago

Showing 4361-4380 of 20,493 trials

Single-Sided Deafness and Asymmetric Hearing Loss

NCT04506853

The purpose of the study is to evaluate the long-term safety and effectiveness of cochlear implantation of the approved population in adults and children with single-sided deafness and asymmetric hearing loss.

Hearing Loss, UnilateralHearing Loss, Sensorineural

Med-El Corporation65 participantsStarted Feb 2021

Chicago, Illinois, United States • Iowa City, Iowa, United States • New York, New York, United States +3 more locations

RECRUITINGPhase 22.2 miles

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

NCT04561206

This phase II trial investigates how well brentuximab vedotin and nivolumab work in treating patients with classical Hodgkin lymphoma that has come back after initial treatment (relapsed) or has not responded to initial treatment (refractory). Brentuximab vedotin is a monoclonal antibody, brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to CD30 positive cancer cells in a targeted way and delivers vedotin to kill them. Nivolumab is an antibody that enhances the immune system to better fight Hodgkin lymphoma cells. Giving brentuximab vedotin and nivolumab may be able to defer stem cell transplant treatment and spare the considerable cost and toxicity on transplantation.

Relapsed Classic Hodgkin Lymphoma

City of Hope Medical Center31 participantsStarted Nov 2021

Duarte, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +2 more locations

Single-Sided Deafness and Asymmetric Hearing Loss

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

Find Trials by Condition in Chicago

The Course of Hip Flexion Weakness Following LLIF or ALIF

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLC

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

Computerized Registry of Patients With Venous Thromboembolism (RIETE)

Telehealth as a Modality to Increase the Uptake of PrEP Services in Black and Latino: "e-PrEP"

A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)

Weight Bearing After Pelvis and Acetabulum Fracture Fixation

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

Beacon Sensors and Telerehabilitation to Assess and Improve Use of Devices (BeST-AID) for Low Vision

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery

Comparing Hypothermic Temperatures During Hemiarch Surgery

An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)