Clinical Trials in California

Showing 4421-4440 of 11,359 trials

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

NCT03110822

This is a phase 1, multicenter, open-label study evaluating the safety and efficacy of ruxolitinib, steroids and lenalidomide among MM patients who currently show progressive disease.

Multiple Myeloma

Oncotherapeutics134 participantsStarted Feb 2017

Alhambra, California, United States • Bakersfield, California, United States • Encinitas, California, United States +10 more locations

TERMINATEDPhase 3130 miles

A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer

NCT01849874

The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer) is a Phase 3 study during which patients with recurrent or persistent low-grade serous (LGS) carcinomas of the ovary, fallopian tube or primary peritoneum will receive either investigational study drug MEK162 or a chemotherapy chosen by the physician (liposomal doxorubicin, paclitaxel or topotecan). Patients will be followed to compare the effectiveness of the study drug to that of the selected chemotherapies. Patients may be eligible to crossover from physician's choice chemotherapy to MEK162 if they meet certain inclusion criteria including centrally confirmed disease progression. Approximately 360 patients from North America, Europe and Australia will be enrolled in this study.

Low-grade Serous Ovarian CancerLow-grade Serous Fallopian Tube CancerLow-grade Serous Peritoneal Cancer

Pfizer341 participantsStarted Jun 2013

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Scottsdale, Arizona, United States +223 more locations

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer

Find Trials by Condition in California

Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy

SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes

Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma

A Device Study for the Treatment of Acne

Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV

Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma

Efficacy and Safety of Sirolimus in LAM

Performance and Safety of Biology-Guided Radiotherapy Using the RefleXion Medical Radiotherapy System (BIOGUIDE-X)

A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight

Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation

Efficacy and Safety of Reparixin in Pancreatic Islet Auto-transplantation

A Trial Investigating Safety and Efficacy of Treatment With BAY94-9027 in Severe Hemophilia A

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Diabetic Peripheral Neuropathic Pain

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Osteoarthritis

FOLFIRI Alone Versus FOLFIRI Plus Bevacizumab Versus FOLFIRI Plus E7820 as Second-Line Therapy in Patients With Locally Advanced or Metastatic Colorectal Cancer

The Chocolate Touch Study

A Non-interventional Study for the Collection of Biospecimens From Patients With Parkinson's Disease