Clinical Trials in Boston

Showing 521-540 of 15,299 trials

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

NCT03478514

The proposed study is a single-arm, multi-center, open-label phase II study of the combination of palbociclib and ibrutinib in patients with previously treated mantle cell lymphoma to evaluate the efficacy of this combination, with the primary objective of the study being to assess median PFS and the secondary objectives to include ORR, CR, DOR, OS and toxicity. Subjects will be enrolled and treated with palbociclib and ibrutinib with each cycle of therapy being 28 days. Treatment will be based on the recommended phase II dose (RP2D) from the phase I combination trial.

Mantle Cell LymphomaB Cell Lymphoma

Alliance Foundation Trials, LLC.39 participantsStarted Sep 2018

Duarte, California, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +6 more locations

RECRUITING< 1 mile

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

NCT06839469

The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended periods of time, in DMD and SMA.

Spinal Muscular Atrophy Type 3Duchenne Muscular Dystrophy (DMD)

Columbia University106 participantsStarted May 2024

Palo Alto, California, United States • Boston, Massachusetts, United States • New York, New York, United States

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

Find Trials by Condition in Boston

CHAMPION-AF Clinical Trial

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

Rituximab/Bendamustine + Rituximab/Cytarabine for Mantle Cell Lymphoma

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism

Dance Study for Post-surgical Pain in Breast Cancer Survivors

Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both

Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

Understanding Needs of Older Patients Prior to Starting Cancer Treatment

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

A Study About the Long-Term Safety of TAK-881 in People With Primary Immunodeficiency Diseases

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

A Study of ZL-1310 in Participants With Selected Solid Tumors