Clinical Trials in Boston

Showing 3721-3740 of 15,299 trials

Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder

NCT02375880

DKN-01 is a humanized monoclonal antibody (Mab) with neutralizing activity against Dkk-1 and is being developed as an anti-neoplastic agent. This study is designed to evaluate the safety, tolerability, pharmacokinetics, and anti-tumor activity of DKN-01 in combination with gemcitabine and cisplatin in patients with carcinoma primary to the intra- or exta-hepatic biliary system or gallbladder.

Carcinoma of Intrahepatic and Extra-hepatic Biliary SystemCarcinoma of GallbladderBile Duct Cancer+1 more

Leap Therapeutics, Inc.51 participantsStarted Jun 2015

Los Angeles, California, United States • New Haven, Connecticut, United States • Boston, Massachusetts, United States +6 more locations

Active Not Recruiting< 1 mile

A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)

NCT05398341

The purpose of the Bridge Registry is to assess real-world performance of the FDA approved BEAR Implant.

Anterior Cruciate Ligament Injuries

Miach Orthopaedics300 participantsStarted Feb 2023

Redwood City, California, United States • Steamboat Springs, Colorado, United States • Orlando, Florida, United States +6 more locations

Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder

A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)

Find Trials by Condition in Boston

An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis (AD)

Multicenter Symphony IL-6 Monitoring Sepsis ICU Study

Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas

A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas

A Study of DKN-01 and Lenalidomide/Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

A Study in Adults and Adolescents With Angelman Syndrome (STARS)

A Study to Evaluate the Incidence of Clinically Suspicious Lambert-Eaton Myasthenic Syndrome (LEMS) in Subjects Diagnosed With Small Cell Lung Cancer (SCLC)

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate

Connect® MM- The Multiple Myeloma Disease Registry

Strength for U in Relationship Empowerment

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)

Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS

A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

Study of Inupadenant (EOS100850) With Chemotherapy as Second Line Treatment for Nonsquamous Non-small Cell Lung Cancer

The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)

A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer