Clinical Trials in Boston

Showing 2521-2540 of 15,299 trials

Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder

NCT06374264

The purpose of this proof of concept study is to assess the acceptability and safety of MR-C-014 in persons with Neuromyelitis optica spectrum disorder (NMOSD) who have a gait deficit.

Neuromyelitis Optica Spectrum Disorder

MedRhythms, Inc.30 participantsStarted Nov 2024

Atlanta, Georgia, United States • Boston, Massachusetts, United States

COMPLETEDNA< 1 mile

Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia

NCT02703090

The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to noxious stimulation.

AnesthesiaPain

Boston Children's Hospital44 participantsStarted Oct 2016

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

Nirogacestat in Ovarian Granulosa Cell Tumors

NCT05348356

This phase 2 clinical trial will study the effectiveness of nirogacestat in ovarian granulosa cell tumors (OvGCTs). Nirogacestat is a gamma secretase inhibitor (GSI) which is hypothesized to decrease the growth and activity of ovarian granulosa tumors.

Ovarian Granulosa-Stromal TumorOvarian Granulosa Cell TumorOvarian Cancer

SpringWorks Therapeutics, Inc.53 participantsStarted Aug 2022

Los Angeles, California, United States • Los Angeles, California, United States • Orlando, Florida, United States +18 more locations

Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder

Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia

Nirogacestat in Ovarian Granulosa Cell Tumors

Find Trials by Condition in Boston

Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Early Life Stress and Depression: Molecular and Functional Imaging

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Study 1.2 (Stress Manipulation)

A Study of HBS-201 (Pitolisant Delayed-release)

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014)

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma.

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.

A Study of Zigakibart in Adults With IgA Nephropathy

A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors

A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma