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Clinical Trials in Atlanta | 19,805 Studies Near You | Clareo Health

Clinical Trials LocationsAtlanta

Clinical Trials in Atlanta

Discover 19,805 clinical trials near Atlanta, Georgia. Find research studies in your area.

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Showing 18001-18020 of 19,805 trials

TERMINATEDPhase 2< 1 mile

Efficacy and Safety of IPI-504 With Trastuzumab Pretreated, Locally Advanced or Metastatic HER2 Positive Breast Cancer

NCT00817362

The purpose of this study is to see if IPI-504 in combination with trastuzamab is an effective treatment in HER2 positive metastatic breast cancer

Breast CancerHER2 Positive Breast CancerMetastatic Breast Cancer+1 more

Infinity Pharmaceuticals, Inc.29 participantsStarted Mar 2009

Palm Springs, California, United States • Boca Raton, Florida, United States • Davie, Florida, United States +8 more locations

COMPLETEDPhase 1< 1 mile

Phase 1 Study of MDX-1401 in Patients With CD30-positive Refractory/Relapsed Hodgkin's Lymphoma

NCT00634452

To establish the safety and tolerability profile of MDX-1401 in patients with relapsed or refractory Hodgkin's Lymphoma (HL).

Hodgkin's Lymphomas

Bristol-Myers Squibb22 participantsStarted Feb 2008

Atlanta, Georgia, United States • Chicago, Illinois, United States • New York, New York, United States +3 more locations

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Data from ClinicalTrials.govTerms

COMPLETED< 1 mile

Evaluation of Low Source of Signal in SCOUT DS

NCT01339637

The overall objective of this study is to increase the number of dark skin tone individuals in the data set and evaluate if this increase in dark skin tone data has an impact on the accuracy of the SCOUT DS Diabetes Risk Score (DRS).

Metabolic SyndromeImpaired Glucose ToleranceGestational Diabetes

VeraLight, Inc.196 participantsStarted Apr 2011

Birmingham, Alabama, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +2 more locations

TERMINATEDPhase 2< 1 mile

Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects

NCT00734435

The purpose of this study is to determine if zonisamide SR will prevent weight gain in schizophrenic subjects who take olanzapine (Zyprexa)

SchizophreniaSchizoaffective DisorderSchizophreniform Disorder

Orexigen Therapeutics, Inc26 participantsStarted Sep 2008

National City, California, United States • Orange, California, United States • San Diego, California, United States +6 more locations

COMPLETEDPhase 25.6 miles

A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis

NCT01052194

This study is designed to evaluate safety and assess initial efficacy of VX-509, a JAK3 inhibitor, for treatment of subjects with active RA. This study will assess the clinical response of 4 doses of VX-509 compared to placebo when administered for 12 weeks to patients with active RA. The study will also evaluate the safety and tolerability of VX-509 compared to placebo when administered for 12 weeks to subjects with active RA.

Rheumatoid Arthritis

Vertex Pharmaceuticals Incorporated206 participantsStarted Feb 2010

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Peoria, Arizona, United States +45 more locations

COMPLETED22 miles

Fibromyalgia Health Outcome Study on Cost of Treatments

NCT00725101

The Real World Examination of Fibromyalgia: Longitudinal Evaluation of Costs and Treatments (REFLECTIONS) Study is a 12-month, prospective observational study that will be utilized in approximately 58 care settings in the United States (US) and Puerto Rico. It is designed to examine treatment patterns and health outcomes of adult participants diagnosed by their physician with fibromyalgia (FM) and who are starting any "new pharmacologic agent" for FM. The primary benefit of this study is enhanced understanding of the disease state of FM and the role that pharmacologic treatment plays, which may help to optimize management of FM. This study will address current gaps in a rapidly growing body of literature on FM.

Eli Lilly and Company1,700 participantsStarted Jun 2008

Hot Springs, Arkansas, United States • Santa Barbara, California, United States • Danbury, Connecticut, United States +55 more locations

COMPLETEDPhase 483 miles

A Study of the Effects of RoActemra/Actemra on Vaccination in Patients With Rheumatoid Arthritis on Background Methotrexate (VISARA)

NCT01163747

This randomized, parallel-group, open-label study will evaluate the effect of Actemra (tocilizumab) on vaccination in patients with active rheumatoid arthritis who have an inadequate response to methotrexate and who have had an inadequate clinical response or were intolerant to treatment with one or more anti-tumor necrosis factor (anti-TNF) therapies.

Rheumatoid Arthritis

Genentech, Inc.91 participantsStarted Sep 2010

Anniston, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +44 more locations

COMPLETED137 miles

Xpress Digital Mammography System Images for Computer Aided Detection Development

NCT01061138

The primary objective of this study is to acquire digital mammography images produced by the Xpress Digital Mammography System in order to develop Computer Aided Detection software and systems.

Konica Minolta Medical Imaging, USA597 participantsStarted Feb 2010

Waterbury, Connecticut, United States • Miami, Florida, United States • Iowa City, Iowa, United States +2 more locations

TERMINATEDPhase 2140 miles

Study to Evaluate the Safety and Efficacy of the Renal Assist Device in Patients With Acute Renal Failure

NCT00280072

* The purpose of this study is to evaluate the safety and efficacy of the RAD to determine whether the RAD is effective in reducing mortality in patients with Acute Renal Failure due to Acute Tubule Necrosis and to evaluate the safety of the RAD * If the RAD works normally when used for as long as 72 hours * If the RAD will provide added benefits to normal CVVH therapy for patients with Acute Renal Failure

Kidney Failure, Acute

RenaMed BiologicsStarted Jan 2006

Birmingham, Alabama, United States • Denver, Colorado, United States • Washington D.C., District of Columbia, United States +13 more locations

COMPLETEDPhase 2140 miles

Study of Lornoxicam or Placebo for Acute Treatment of the Headache of Migraine.

NCT00293657

To determine whether a single dose of intravenous lornoxicam is superior to intravenous placebo for the acute treatment of moderate or severe headache associated with a single migraine attack in patients with a history of migraine. Two-thirds of patients in this study will receive a single dose of intravenous lornoxicam (8mg or 16 mg) and one-third of patients will receive a single dose of an intravenous placebo.

Headache (Migraine)

POZEN150 participantsStarted Dec 2005

Birmingham, Alabama, United States • Mobile, Alabama, United States • Little Rock, Arkansas, United States +20 more locations

COMPLETEDPhase 2140 miles

Open-Label Study To Evaluate the Safety and Efficacy of the Renal Assist Device In Patients With Acute Renal Failure

NCT00511407

Although conventional hemodialysis removes waste products and corrects fluid imbalance, it does not replace critical absorptive, metabolic, endocrine, and immunologic functions performed by healthy renal tubule cells. This trial involving patients with acute renal failure evaluates the efficacy and safety of an extracorporeal renal assist device (RAD) containing human renal tubule cells connected to a conventional hemodialysis circuit. It is hypothesized that short-term (72-h) use of this cell therapeutic device will improve survival of ARF patients compared to patients receiving only conventional continuous renal replacement therapy.

Acute Renal Failure

RenaMed Biologics58 participantsStarted Mar 2004

Birmingham, Alabama, United States • Augusta, Georgia, United States • Chicago, Illinois, United States +10 more locations

COMPLETEDPhase 1/2140 miles

Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC)

NCT00431015

The purpose of this study is to determine the safety, tolerability and maximum tolerated dose of IPI-504 in patients with non-small cell lung cancer (NSCLC). The study will examine how IPI-504 is absorbed, distributed, metabolized and eliminated by the body. The study will also evaluate the anti-tumor activity of IPI-504.

Infinity Pharmaceuticals, Inc.88 participantsStarted Jan 2007

Los Angeles, California, United States • New Haven, Connecticut, United States • Miami, Florida, United States +8 more locations

COMPLETEDPhase 2140 miles

Zonisamide SR Plus Bupropion SR Combination Therapy in Subjects With Obesity

NCT00709371

The purpose of this study is determine if the combination of zonisamide SR and bupropion SR are is more effective than either drug given alone or placebo in the treatment of obesity.

Orexigen Therapeutics, Inc729 participantsStarted Jul 2008

Fairhope, Alabama, United States • La Jolla, California, United States • Denver, Colorado, United States +17 more locations

COMPLETED143 miles

Screening for Early Evidence of Diabetes

NCT00614783

This is a pivotal study to determine the accuracy of a new device (SCOUT) in screening persons for pre-diabetes or diabetes. SCOUT will be compared to the standard screening test (Fasting Plasma Glucose), using the Oral Glucose Tolerance Test as the reference standard. SCOUT uses a rapid, noninvasive, light-based technology to measure the concentration of chemicals in the skin called advanced glycation endproducts (AGEs). Several studies have demonstrated that AGEs accumulate in skin faster in individuals with poor control of blood sugar. Persons will be eligible for the study if they are 'at risk' for diabetes based on their age and other risk factors as defined by the American Diabetes Association.

Diabetes Mellitus, Type 2

VeraLight, Inc.3,478 participantsStarted May 2007

Huntsville, Alabama, United States • San Diego, California, United States • San Diego, California, United States +12 more locations

COMPLETEDPhase 4215 miles

Epoprostenol for Injection in Pulmonary Arterial Hypertension - Extension of AC-066A401

NCT01105117

This is an open-label, non-randomized extension to study AC-066A401. The study will assess safety and tolerability of ACT-385781A and Flolan (epoprostenol sodium) while providing a means for continuing treatment after ending participation in study AC-0066A401.

Pulmonary Arterial Hypertension

Actelion2 participantsStarted May 2010

La Jolla, California, United States • Aurora, Colorado, United States • Durham, North Carolina, United States +4 more locations

COMPLETEDPhase 3285 miles

Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission

NCT00099359

Giving anti-HIV medications to babies born of HIV positive mothers right after birth can lower the babies' risk of contracting HIV. This study will assess the safety and efficacy of two different combinations of anti-HIV medications compared to a one drug standard regimen in preventing mother to baby transmission. The one drug standard treatment and two combinations to be studied are: 1) zidovudine, 2) zidovudine/nevirapine and 3) zidovudine/lamivudine/nelfinavir.

Disease Transmission, VerticalVertical Human Immunodeficiency Virus TransmissionHIV Infections

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)1,735 participantsStarted Feb 2004

Long Beach, California, United States • Gainesville, Florida, United States • Jacksonville, Florida, United States +14 more locations

COMPLETEDPhase 2321 miles

Safety and Efficacy of Once-daily Oral Administrations of TZP-102 for Gastroparesis in Patients With Diabetes Mellitus

NCT00889486

The purpose of this study is to evaluate the effect of TZP-102 on gastric emptying rate, gastroparesis symptoms and health-related quality of life in diabetic patients with gastroparesis.

GastroparesisDiabetes Mellitus

Tranzyme, Inc.92 participantsStarted Apr 2009

Long Beach, California, United States • Los Angeles, California, United States • San Francisco, California, United States +20 more locations

COMPLETEDPhase 3337 miles

Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia

NCT00136084

The purpose of this study is to compare the effectiveness of two multi-agent chemotherapy regimens using different dosages of cytarabine to eliminate all detectable leukemia.

Leukemia, Myelocytic, Acute

St. Jude Children's Research Hospital238 participantsStarted Aug 2002

Palo Alto, California, United States • Boston, Massachusetts, United States • Detroit, Michigan, United States +5 more locations

WITHDRAWNPhase 3402 miles

6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)

NCT00738738

This is an open-label, multi-site, 6-month study of an investigational compound in elderly outpatients, age 65 years old or above, to assess the long-term safety and tolerability of the compound in the treatment of elderly subjects with Generalized Anxiety Disorder (GAD).

Generalized Anxiety Disorder

PfizerStarted Jan 2009

Orlando, Florida, United States • Prairie Village, Kansas, United States

COMPLETEDPhase 3587 miles

A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAX

NCT00314145

The purpose of this study is to determine non-inferiority in seroconversion and to compare the safety and tolerability between ChimeriVaxTM-JE and JE-VAX to the respective homologous virus strain after completion of vaccination course.

Japanese Encephalitis

Sanofi820 participantsStarted Nov 2005

Chicago, Illinois, United States • Shawnee Mission, Kansas, United States • Missoula, Montana, United States +7 more locations

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