Rheumatoid Arthritis Clinical Trials

Showing 1581-1600 of 40,629 trials

Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure

NCT07463885

Acute hypoxemic respiratory failure may progress to acute respiratory distress syndrome, a life-threatening condition that often requires mechanical ventilation. The optimal ventilation strategy in this patient population remains uncertain. The SVALBARD trial is a feasibility and pilot study designed to compare spontaneous versus controlled mechanical ventilation in patients with acute hypoxemia respiratory failure. The primary objective is to assess the feasibility of the study procedures and interventions, while also collecting descriptive data on key clinical variables to inform the design of a future randomized controlled trial.

Acute Respiratory Distress Syndrome (ARDS)Acute Hypoxemic Respiratory Failure

Oslo University Hospital80 participantsStarted Sep 2026

Active Not RecruitingPhase 1

A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT02123758

The purpose of this study is to investigate potential drug-drug interaction (DDI) between JNJ-56021927 and abiraterone acetate and between JNJ-56021927 and prednisone, determine safety of the combination and evaluate in a descriptive manner the efficacy in these participants. It will also, potentially provide dosing recommendations for abiraterone acetate in future studies when combined with JNJ-56021927.

Prostatic NeoplasmsMetastatic Castration-Resistant Prostate Cancer

Aragon Pharmaceuticals, Inc.57 participantsStarted Jul 2014

Los Angeles, California, United States • San Francisco, California, United States • Houston, Texas, United States +4 more locations

Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure

A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer

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