Rheumatoid Arthritis Clinical Trials

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Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

NCT04221750

The continuing increase in prevalence of obesity in older adults including many older Veterans has become a major health concern. The clinical trial will test the central hypothesis that a multicomponent intervention consisting of lifestyle therapy (diet-induced weight loss and exercise training) plus metformin will be the most effective strategy for reversing sarcopenic obesity and frailty in older Veterans with obesity.

FrailtySarcopenic ObesityAging

VA Office of Research and Development114 participantsStarted May 2021

Houston, Texas, United States

TERMINATEDNA

Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM)

NCT04801472

This is a monocentric, non-randomized, prospective, in silico feasibility study conducted by Strasbourg Europe Cancerology Institute. The purpose of this study is to evaluate the optimisation of potential dental implant sites protection, without degrading tumor volume coverage, through designation of potential dental implant sites before volume delineation and dosimetry calculations in patients with oropharyngeal or oral cavity squamous cell carcinoma treated by radiotherapy.

Squamous Cell Carcinoma of Head and NeckOropharyngeal Squamous Cell CarcinomaOral Cavity Squamous Cell Carcinoma

Institut de cancérologie Strasbourg Europe8 participantsStarted May 2021

Strasbourg, France

Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM)

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