Rheumatoid Arthritis Clinical Trials in Los Angeles

Showing 1781-1800 of 2,731 trials

CNS10-NPC-GDNF for the Treatment of ALS

NCT02943850

The investigator is examining the safety of transplanting cells that have been engineered to produce a growth factor into the spinal cord of patients with Amyotrophic Lateral Sclerosis (ALS). The cells are called neural progenitor cells, which are a type of stem cell that can become several different types of cells in the nervous system. These cells have been derived to specifically become astrocytes, which is a type of neuronal cell. The growth factor is called glial cell line-derived neurotrophic factor, or GDNF. GDNF is a protein that promotes the survival of many types of neuronal cells. Therefore, the cells are called "CNS10-NPC-GDNF." The investigational treatment has been tested in animals, but it has not yet been tested in people. In this study, we want to learn if CNS10-NPC-GDNF cells are safe to transplant into the spinal cords of people.

Amyotrophic Lateral Sclerosis

Cedars-Sinai Medical Center18 participantsStarted Apr 2017

Los Angeles, California, United States

TERMINATEDPhase 3< 1 mile

Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis

NCT02138838

The primary objective was to evaluate the efficacy of cinacalcet for reducing the plasma intact parathyroid hormone (iPTH) level by ≥ 30%.

Chronic Kidney Disease, Secondary Hyperparathyroidism

Amgen55 participantsStarted Nov 2014

Los Angeles, California, United States • Wilmington, Delaware, United States • Atlanta, Georgia, United States +57 more locations

CNS10-NPC-GDNF for the Treatment of ALS

Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis

Rheumatoid Arthritis Trials in Other Cities

Study to Evaluate Cinacalcet in Children With Chronic Kidney Disease

Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)

5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab

The Effects of Manipulating Expectations in a Gratitude Intervention

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion

Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain

A Safety Study of Galcanezumab in Participants With Migraine, With or Without Aura

Clinical Investigation of the Next Generation Intraocular Lens

Sargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By Surgery

Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Screening

Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy

Fecal Microbiota Transplantation for the Treatment of Recurrent Urinary Tract Infections

A Study of Galcanezumab (LY2951742) in Adults With Treatment-Resistant Migraine

Viral Triggers in Pediatric Lung Transplantation

Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular Degeneration

Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

Other Conditions in Los Angeles