Rheumatoid Arthritis Clinical Trials in Los Angeles

Showing 461-480 of 2,731 trials

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

NCT01659606

Dyskeratosis congenita is a disease that affects numerous parts of the body, most typically causing failure of the blood system. Lung disease, liver disease and cancer are other frequent causes of illness and death. Bone marrow transplantation (BMT) can cure the blood system but can make the lung and liver disease and risk of cancer worse, because of DNA damaging agents such as alkylators and radiation that are typically used in the procedure. Based on the biology of DC, we hypothesize that it may be possible to avoid these DNA damaging agents in patients with DC, and still have a successful BMT. In this protocol we will test whether a regimen that avoids DNA alkylators and radiation can permit successful BMT without compromising survival in patients with DC.

Dyskeratosis CongenitaHoyeraal Hreidarsson SyndromeRevesz Syndrome+1 more

Boston Children's Hospital40 participantsStarted Jul 2012

Los Angeles, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +11 more locations

Active Not RecruitingPhase 3< 1 mile

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

NCT05949593

This Phase 3, multicenter, double-masked, parallel-group, placebo-controlled, randomized, fixed-dose clinical study is designed to evaluate the efficacy and safety of tinlarebant (LBS-008) in subjects diagnosed with GA.

Geographic Atrophy

Belite Bio, Inc429 participantsStarted Jul 2023

Phoenix, Arizona, United States • Arcadia, California, United States • Beverly Hills, California, United States +46 more locations

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

Rheumatoid Arthritis Trials in Other Cities

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

Prevention of Colorectal Cancer Through Multiomics Blood Testing

Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial Disc

Investigation of the Two Level Simplify® Cervical Artificial Disc

Quadratus Lumborum Block for Total Hip Arthroplasty

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

An Extension Study of RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis

Acute Hip Fracture Study in Patients 65 Years or Greater

Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC

Integrated Health Care for PTSD

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study

Olaparib In Metastatic Breast Cancer

Other Conditions in Los Angeles