Rheumatoid Arthritis Clinical Trials in Los Angeles

Showing 381-400 of 2,731 trials

COMPASSION S3 Post-Approval Study

NCT04860765

This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve in the pulmonic position with a clinical indication for intervention.

Complex Congenital Heart DefectDysfunctional RVOT ConduitPulmonary Valve Insufficiency+2 more

Edwards Lifesciences150 participantsStarted Apr 2021

Birmingham, Alabama, United States • Los Angeles, California, United States • Aurora, Colorado, United States +16 more locations

RECRUITINGPhase 2< 1 mile

Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

NCT05534646

This is an open-label, multi-site study of apalutamide with carotuximab in patients who have progressed on androgen receptor signaling inhibitor (ARSI) therapy. This study will begin with a safety assessment in the first 10 subjects (part 1: Safety Lead-in). If the combination is deemed safe, the trial will proceed to the Phase II stage. The purpose of this study is to compare progression free survival (PFS) between patients receiving apalutamide and apalutamide + carotuximab using Response Evaluation Criteria in Solid Tumors (RECIST 1.1) and Prostate Cancer Working Group 3. The secondary objectives are to describe adverse events related to the intervention, overall response rate (ORR), proportion of patients resistant to apalutamide that benefit from the addition of carotuximab, and to determine the ORR, radiographic PFS, and biochemical PFS in the overall population.

Castration-resistant Prostate Cancer

Edwin Posadas, MD100 participantsStarted Dec 2023

Duarte, California, United States • Los Angeles, California, United States • Salt Lake City, Utah, United States

COMPASSION S3 Post-Approval Study

Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

Rheumatoid Arthritis Trials in Other Cities

Study of Axicabtagene Ciloleucel Given With Steroids In Participants With Relapsed Or Refractory Large B-Cell Lymphoma

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

TVMR With the INNOVALVE System Trial - Early Feasibility Study

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD

HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis

Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

A Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV) Vaccine in Adult Participants ≥60 Years of Age

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Other Conditions in Los Angeles