Rheumatoid Arthritis Clinical Trials in Chicago

Showing 621-640 of 3,348 trials

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

NCT06239116

The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairment

Hypothalamic ObesityPrader-Willi SyndromePWS

Rhythm Pharmaceuticals, Inc.150 participantsStarted Mar 2024

Birmingham, Alabama, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +4 more locations

Active Not RecruitingPhase 22.2 miles

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

NCT05241860

This phase II trial examines antiandrogen therapy interruptions in patients with hormone-sensitive prostate cancer that has spread to other places in the body (metastatic) responding exceptionally well to androgen receptor-pathway inhibitor therapy. The usual treatment for patients with metastatic prostate cancer is to receive hormonal medications including a medication to decrease testosterone levels in the body and a potent oral hormonal medication to block growth signals from male hormones (like testosterone) in the cancer cells. Patients whose cancer is responding exceptionally well to this therapy may take a break from these medications according to their doctor's guidance. This trial may help doctors determine if stopping treatment can allow for testosterone recovery.

Castration-Sensitive Prostate CarcinomaMetastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8+2 more

Alliance for Clinical Trials in Oncology79 participantsStarted Nov 2022

Phoenix, Arizona, United States • Fort Smith, Arkansas, United States • Little Rock, Arkansas, United States +323 more locations

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

Rheumatoid Arthritis Trials in Other Cities

Lumbar Interbody Implant Study

A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc

A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age

NuVasive® ACP System Study

Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

SMART TRENDS Study

Spreading Depolarizations in Traumatic Brain Injury

A Study to Compare How Well Gadoquatrane Works and Its Safety With an Already Available Contrast Agent for MRI in People With Any Known or Suspected Problems of the Body (Except Brain or Spinal Cord-related Problems)

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

iAmHealthy Clinical Practice Guideline (CPG)

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

Other Conditions in Chicago