Multiple Sclerosis Clinical Trials in Philadelphia

Showing 101-120 of 634 trials

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab

NCT04998851

This study will evaluate the pharmacokinetics of ocrelizumab in the breastmilk of lactating women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) \[in line with the locally approved indications\] treated with ocrelizumab, by assessing the concentration of ocrelizumab in mature breastmilk, as well as the corresponding exposure and pharmacodynamic effects (blood B cell levels) in the infants.

Multiple SclerosisClinically Isolated Syndrome

Hoffmann-La Roche26 participantsStarted Sep 2021

San Francisco, California, United States • Aurora, Colorado, United States • Chicago, Illinois, United States +5 more locations

Active Not RecruitingPhase 1/2< 1 mile

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

NCT05651022

INDP-D101 is a Phase 1/2, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of Decoy20 as monotherapy and in combination with tislelizumab in patients with locally advanced or metastatic solid tumors.

Solid Tumor, AdultHCC - Hepatocellular CarcinomaCRC (Colorectal Cancer)+5 more

Indaptus Therapeutics, Inc120 participantsStarted Feb 2023

Los Angeles, California, United States • Newport Beach, California, United States • Atlanta, Georgia, United States +9 more locations

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

Multiple Sclerosis Trials in Other Cities

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Multi-Institutional Transgender & Gender-Diverse Breast Cancer Study

Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)

A Comparison of Platinum-based Therapy With TSR-042 and Niraparib Versus Standard of Care (SOC) Platinum-based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer

A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

A Single Arm Study Evaluating the Efficacy, Safety and Tolerability of Ofatumumab in Patients With Relapsing Multiple Sclerosis

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

Effect of Support for Low-Income Mothers of Preterm Infants

A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Prostate Active Surveillance Study

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Other Conditions in Philadelphia