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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 480 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 480 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 281-300 of 480 trials

CompletedA Study of RGX-104 in Patients With Advanced Lung & Endometrial CancerStudy RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor (LXR), as a single agent and…NCT02922764·Tucson, Arizona and 20 others RecruitingA Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung CancerA study of tolododekin alfa (also known as ANK-101) administered in combination with an anti-programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) antibody…NCT07027514·Coral Gables, Florida and 10 others

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Data from ClinicalTrials.govTerms

CompletedPaclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00021333·Flemington, New Jersey and 17 others

CompletedA Study of Erlotinib (Tarceva) After Surgery With or Without Adjuvant Chemotherapy in Non-Small Cell Lung Carcinoma (NSCLC) Patients Who Have Epidermal Growth Factor Receptor (EGFR) Positive TumorsThis is a study to evaluate the effectiveness of erlotinib compared with a placebo sugar pill following complete surgical removal of the tumor with or without chemotherapy after…NCT00373425·Birmingham, Alabama and 294 others

CompletedMonoclonal Antibody ABX-EGF in Treating Patients With Renal (Kidney), Prostate, Pancreatic, Non-Small Cell Lung, Colon or Rectal, Esophageal, or Gastroesophageal Junction CancerRATIONALE: Monoclonal antibodies such as ABX-EGF can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.NCT00004879·Los Angeles, California and 1 other

RecruitingKEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)This study is referred to as the "umbrella master protocol" for pembrolizumab (MK-3475) in the treatment of non-small cell lung cancer (NSCLC).NCT04165798·Gilbert, Arizona and 46 others

WithdrawnSotorasib in KRAS G12C Mutated, Resectable, Stage Ib-IIIA NSCLCThis is a single arm study, conducted at two centers, of neoadjuvant sotorasib in treatment naïve patients with stage Ib-IIIa NSCLC. The study will accrue 25 patients in all.NCT05400577·Philadelphia, Pennsylvania

CompletedA Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced MalignanciesThis is a Phase 1, open-label, first-in-human (FIH) dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and…NCT02571036·Scottsdale, Arizona and 25 others

CompletedIressa Expanded Access Program (EAP)A program for patients with non small cell lung cancer who may benefit from Iressa, but cannot enter another clinical trial due to them not being eligible, or for whom no trials…NCT00034879·Alabaster, Alabama and 625 others

CompletedABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic CancerThe drug ABR-217620 is a combination of two proteins, one that recognizes tumor cells and one that triggers an attack on the tumor cells by activating some white blood cells…NCT00056537·Philadelphia, Pennsylvania and 2 others

CompletedStudy of the Glutaminase Inhibitor CB-839 in Solid TumorsMany tumor cells, in contrast to normal cells, have been shown to require the amino acid glutamine to produce energy for growth and survival.NCT02071862·San Francisco, California and 12 others

RecruitingStudy of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsThis is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity…NCT05176483·Phoenix, Arizona and 121 others

Active not recruitingStudy of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung CancerThis is an open label multi center trial to determine the safety and efficacy of ceritinib in combination with nivolumab in ALK-positive NSCLC patientsNCT02393625·Scottsdale, Arizona and 11 others

CompletedVaccine Therapy Plus Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer That Has Been Completely Removed in SurgeryRATIONALE: Vaccines may make the body build an immune response to kill tumor cells. Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00006470·Birmingham, Alabama and 236 others

CompletedAn Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung CancerThis is a phase II, open-label, multicenter, randomized study to evaluate the efficacy and safety of GSK1120212 compared with docetaxel in the second line setting for subjects…NCT01362296·Scottsdale, Arizona and 59 others

CompletedRucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)This phase II Lung-MAP trial studies how well rucaparib works in treating patients with genomic loss of heterozygosity (LOH) high and/or deleterious BRCA1/2 mutation stage IV…NCT03845296·Mobile, Alabama and 949 others

CompletedA Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced MalignanciesThe primary purpose of this study is to assess the safety and tolerability of AB801 in participants with advanced malignancies, and to determine a recommended AB801 dose for…NCT06120075·Denver, Colorado and 9 others

Active not recruitingFirst-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid TumorsThis is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of remzistotug in participants with select…NCT05277051·San Francisco, California and 25 others

CompletedSingle Arm on the Tolerability of Weekly Nab-paclitaxelThe purpose of this study is to evaluate the safety and efficacy of weekly nab-paclitaxel for a second-line treatment in elderly subjects, 70 years of age or greater, with…NCT01702844·Fayetteville, Arkansas and 7 others

UnknownNeoadjuvant Compound 121564 Plus Platinum Doublet Chemotherapy in Non-Small Cell Lung CancerThe purpose of this study is to assess the response rate to neoadjuvant Compound 121564 plus platinum doublet chemotherapy in patients with early stage non-small cell lung cancer.NCT03480230·Amman and 4 others

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Other Conditions in Philadelphia

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma