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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 480 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 480 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 181-200 of 480 trials

Active not recruitingImplementation Strategies for Monitoring Adherence in Real TimeThe objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.NCT04347161·Philadelphia, Pennsylvania CompletedStudy of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)The primary objectives of the study are: * To compare the overall survival (OS) of cemiplimab versus standard-of-care platinum-based chemotherapies in the first-line treatment of…NCT03088540·Albury, New South Wales and 191 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid TumorsPart 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors.NCT04440735·La Jolla, California and 6 others

CompletedPhase II Study of Pembrolizumab After Curative Intent Treatment for Oligometastatic Non-Small Cell Lung CancerThe main purpose of this study is to see how well the experimental drug pembrolizumab (MK-3475) works in people with oligometastatic NSCLC who have already had treatment for their…NCT02316002·Philadelphia, Pennsylvania

TerminatedStudy for Treatment With TH-4000 (Tarloxotinib) in Epidermal Growth Factor Receptor (EGFR) Mutant, T790M-negative Non-small Cell Lung Cancer (NSCLC) PatientsThis phase 2 study is designed to evaluate the safety and activity of TH-4000 a hypoxia-activated prodrug, in patients with EGFR-Mutant, T790M-Negative, Advanced NSCLC.NCT02454842·Los Angeles, California and 11 others

CompletedA Study of Alectinib (CH5424802/RO5424802) in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC)This non-randomized, open-label, multicenter study will evaluate the safety and efficacy of alectinib in participants with ALK-rearranged non-small cell lung cancer who failed…NCT01871805·Birmingham, Alabama and 41 others

CompletedA Study of a Personalized Cancer Vaccine Targeting Shared NeoantigensThe purpose of this study is to evaluate the dose, safety, immunogenicity and early clinical activity of GRT-C903 and GRT-R904, a neoantigen-based therapeutic cancer vaccine, in…NCT03953235·Phoenix, Arizona and 11 others

CompletedCarboplatin Plus Cetuximab for Treatment of Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)This is a phase II study in previously untreated subjects with histologically or cytologically proven stage IIIB/IV NSCLC designed to determine the efficacy of first line…NCT00097214·Bentonville, Arkansas and 7 others

CompletedA Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid TumorsThis study will consider the safety and effectiveness of a study drug, CAN04, in combination with pembrolizumab, in the treatment of incurable or metastatic non-small-cell lung…NCT04452214·Aurora, Colorado and 2 others

CompletedA Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)This was an open-label, nonrandomized, Phase 1/2 study designed to determine the safety, tolerability, and efficacy of epacadostat when given in combination with pembrolizumab and…NCT03085914·Phoenix, Arizona and 15 others

TerminatedRadiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung CancerThis randomized phase III trial is studying whole-brain radiation therapy and stereotactic radiosurgery with or without temozolomide or erlotinib to see how well they work…NCT00096265·Scottsdale, Arizona and 82 others

CompletedStudy of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung CancerIt has been shown in previous studies that the ability to treat lung cancer could be significantly improved by not only targeting the tumor cells directly with chemotherapy, but…NCT00687297·Boca Raton, Florida and 29 others

Active not recruitingTrial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)This is a multicenter, randomized, open-label, international, Phase 3 trial to evaluate the efficacy and safety of acasunlimab in combination with pembrolizumab versus docetaxel…NCT06635824·Tucson, Arizona and 246 others

CompletedAn Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have SpreadThe purpose of the study is to determine safety and effectiveness of experimental medication BMS-986205 when combined with Nivolumab and in combination with both Nivolumab and…NCT02658890·Tucson, Arizona and 46 others

CompletedA Study of Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) TherapyThe main purpose of this study is to determine whether nivolumab + chemotherapy is effective as compared to chemotherapy in the treatment of patients with EGFR mutation, NSCLC who…NCT02864251·Long Beach, California and 108 others

Active not recruitingAZD9291 in Combination With Ascending Doses of Novel TherapeuticsThe purpose of this study is to determine the safety, tolerability and preliminary anti-tumour activity of AZD9291 when given together with AZD6094 or selumetinib in patients with…NCT02143466·Atlanta, Georgia and 41 others

CompletedA Study of ABBV-428, an Immunotherapy, in Subjects With Advanced Solid TumorsThis is an open-label, Phase I, dose-escalation study to determine the recommended Phase 2 dose (RPTD), maximum tolerated dose (MTD), and evaluate the safety and pharmacokinetic…NCT02955251·Scottsdale, Arizona and 14 others

CompletedStereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain MetastasesRATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue.NCT00377156·Phoenix, Arizona and 63 others

CompletedTesting the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 TrialThis phase I trial studies the safety of adding durvalumab to accelerated hypofractionated radiation therapy (ACRT) or conventionally fractionated radiation therapy, as well as…NCT03801902·Atlanta, Georgia and 55 others

CompletedDouble Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLCThe purpose of this study is to find out whether it is better to receive a new drug, MEDI4736, or better to receive no further treatment after surgery (and possibly chemotherapy)…NCT02273375·Gilbert, Arizona and 270 others

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