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Clareo Health | Lung Cancer Clinical Trials in Houston | 825 Studies

Clinical Trials Lung CancerHouston

Lung Cancer Clinical Trials in Houston

Find 825 clinical trials for lung cancer near Houston, Texas. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 461-480 of 825 trials

TerminatedCarboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma HistologyDetermine whether the addition of CP- 751,871 in combination with paclitaxel plus carboplatin prolongs survival in patients with locally advanced (Stage IIIB with pleural…NCT00596830·Florence, Alabama and 279 others

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Data from ClinicalTrials.govTerms

TerminatedA Study of TAS3351 in NSCLC Patients With EGFRmtThis is a first-in-human, open label, Phase 1/2 study to investigate the safety and efficacy of TAS3351 in participants with advanced or metastatic non-small cell lung cancer…NCT05765734·Nashville, Tennessee and 7 others

Active not recruitingStudy of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)The purpose of this study is to compare pembrolizumab (MK-3475) in combination with sacituzumab govitecan with pembrolizumab alone with respect to progression-free survival (PFS)…NCT05609968·Mobile, Alabama and 179 others

CompletedSL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or LymphomasThis is a Phase 1 first in human, open label, multi-center, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, anti-tumor activity and…NCT03894618·Nashville, Tennessee and 4 others

TerminatedPROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid TumorsThe purpose of this first-in-human study of CX-2009 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-2009 in…NCT03149549·Los Angeles, California and 25 others

RecruitingA Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)The study is being conducted to to explore the reasonable dosage and evaluate the efficacy, safety and tolerability of HLX43 (Anti-PD-L1 ADC) in Patients with Advanced Non-small…NCT06907615·Houston, Texas and 1 other

CompletedDasatinib and Erlotinib in Non-Small Cell Lung Cancer (NSCLC)The goal of the Phase I portion of this study is to find the highest tolerable dose of the combination of dasatinib and erlotinib hydrochloride that can be given to patients with…NCT00826449·Houston, Texas

CompletedA First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced CancerIn this study researchers want to gather relevant information regarding the safety of BAY2416964 and how well the drug works in participants with a type of solid tumors that…NCT04069026·New Haven, Connecticut and 16 others

CompletedBevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT01107626·Anniston, Alabama and 433 others

Active not recruitingStudy BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 ExpressionThis clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of…NCT04180371·Encinitas, California and 27 others

RecruitingStudy of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other CancersThis is a phase 1/2, multicenter, open-label study.NCT05098132·Tucson, Arizona and 46 others

TerminatedTarceva Surgery for Resectable Stage IIIA(N2) and IIIB (T4 N2) Non-Small-Cell Lung CancerThe goal of this clinical research study is to learn about the safety and effectiveness of OSI-774 when combined with standard chemotherapy (carboplatin and paclitaxel) before…NCT00063258·Houston, Texas

Active not recruitingStudy of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung CancerThis study is designed to identify the target Non-Small Cell Lung Cancer (NSCLC) population(s) that overexpress c-Met (c-Met+) best suited for telisotuzumab vedotin therapy in the…NCT03539536·Mobile, Alabama and 251 others

CompletedA Dose Frequency Optimization,Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received Up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 WeeksThe primary objective of this study is to compare PFS (progression-free survival) rate at 6 months and at 1 year after randomization, of Nivolumab 480 mg every 4 weeks with…NCT02713867·Birmingham, Alabama and 128 others

RecruitingA Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)The primary objectives are to compare progression-free survival (PFS) and overall survival (OS) in participants who receive sotorasib with platinum doublet chemotherapy versus…NCT05920356·Santa Barbara, California and 423 others

CompletedA Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing TherapyThis global, multicenter, open-label, randomized, controlled study evaluated the efficacy and safety of atezolizumab (an anti-programmed death-ligand 1 \[anti-PD-L1\]…NCT02008227·Bakersfield, California and 207 others

CompletedDocetaxel, Cisplatin, and Erlotinib Hydrochloride in Treating Patients With Stage I-III Non-small Cell Lung Cancer Following SurgeryThis phase I trial studies docetaxel, cisplatin, and erlotinib hydrochloride in treating patients with stage I-III non-small cell lung cancer following surgery.NCT00254384·Houston, Texas

TerminatedRadiation Therapy (XRT) and ZD6474 in Non-Small Cell Lung Cancer (NSCLC)Primary Objectives: * To assess the safety of oral therapy with ZD6474 by evaluating the frequency, severity, and duration of treatment-emergent adverse events in patients with…NCT00745732·Houston, Texas

TerminatedAn Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung CancerThe purpose of this study is to determine whether Nivolumab, in combination with other therapies, is effective in patients with advanced Non-Small Cell lung cancerNCT02750514·Duarte, California and 49 others

RecruitingFirst-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian CancerThe goal of this study is to identify a safe and tolerated dose of the orally administered KIF18A inhibitor ATX-295.NCT06799065·Aurora, Colorado and 10 others

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