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Clareo Health | Lung Cancer Clinical Trials in Houston | 825 Studies

Clinical Trials Lung CancerHouston

Lung Cancer Clinical Trials in Houston

Find 825 clinical trials for lung cancer near Houston, Texas. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 421-440 of 825 trials

Active not recruitingEvaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ TumorsThis study will evaluate safety, pharmacodynamics and biomarkers of subcutaneous (SC) DK210(EGFR) given as monotherapy and in combination with immunotherapy, chemotherapy or…NCT05704985·Duarte, California and 6 others CompletedStudy of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer (NSCLC) (CheckMate 017)The purpose of the study is to compare the overall survival of BMS-936558 as compared with Docetaxel in subjects with squamous cell non-small cell lung cancer (NSCLC), after…NCT01642004·Scottsdale, Arizona and 126 others

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Data from ClinicalTrials.govTerms

RecruitingA Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)This is a Phase II, multi-center, open-label platform study evaluating novel combination treatment options in participants with locally advanced or metastatic NSCLC.NCT07098338·Santa Monica, California and 82 others

Active not recruitingPhase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid TumorThis study is open to adult patients with solid tumors who have a KRAS G12V mutation.NCT06105021·Los Angeles, California and 9 others

Approved for marketingExpanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) ActivationExpanded access for participants with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other…NCT03906331·Goodyear, Arizona and 63 others

CompletedA Study of DF6002 Alone and in Combination With NivolumabThe purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab…NCT04423029·Orange, California and 31 others

CompletedA First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid TumorsThis is a Phase 1, first-in-human, open-label dose-escalation study to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) and assess the DLT of…NCT04045496·Denver, Colorado and 3 others

CompletedTrial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional RecurrenceThe goal of this clinical research study is to learn if, compared with regular x-ray radiation, proton radiation reduces the risk of developing, treatment-related pneumonitis…NCT00915005·Boston, Massachusetts and 1 other

RecruitingBeamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD MutationsBeamion LUNG-3 study evaluates whether zongertinib, an oral HER2-targeted treatment, can improve outcomes compared with standard adjuvant treatment in adults with completely…NCT07195695·Fresno, California and 201 others

CompletedAZD9291 First Time In Patients Ascending Dose StudyThis study will treat patients with advanced NSCLC who have already received at least one course of specific anti-cancer treatment but the tumour has started to re-grow following…NCT01802632·Aurora, Colorado and 44 others

TerminatedRO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast CancerThis randomized phase I/II trial studies the side effects and the best dose of RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) when given together with…NCT01217411·Boston, Massachusetts and 1 other

CompletedStudy of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)The purpose of this study is to evaluate pembrolizumab (MK-3475) subcutaneous (SC) administration as the first-line therapy in the treatment of metastatic squamous and nonsquamous…NCT04956692·Jonesboro, Arkansas and 125 others

Active not recruitingPredicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer TreatmentsThe PROPHETIC study is a prospective, multi-center, international clinical study aimed at developing an algorithm to predict patient outcomes.NCT04056247·Birmingham, Alabama and 40 others

TerminatedTrilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Docetaxel for Metastatic Non-Small Cell Lung Cancer (NSCLC) (PRESERVE 4)This is a randomized, double-blind, placebo-controlled, global, multicenter, Phase 2 trial evaluating the effect of trilaciclib on overall survival when administered prior to…NCT04863248·Phoenix, Arizona and 11 others

Active not recruitingStudy of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)The primary objective of the study is to evaluate the efficacy of osimertinib plus ramucirumab versus osimertinib alone using progression free survival (PFS).NCT03909334·Washington D.C., District of Columbia and 11 others

SuspendedA Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7NPX267 is an antibody drug targeting the inhibitory receptor for B7-H7 (HHLA2) which may control evasion of the immune response in tumors.NCT05958199·Baltimore, Maryland and 6 others

Active not recruitingTocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial CarcinomaThis phase II trial investigates the side effects of tocilizumab, ipilimumab, and nivolumab in treating patients with melanoma, non-small cell lung cancer, or urothelial carcinoma…NCT04940299·Houston, Texas

CompletedDasatinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung CancerDasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00459342·Houston, Texas

Active not recruitingA Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRASThe purpose of the study is to assess the efficacy of durvalumab plus tremelimumab in combination with chemotherapy compared with pembrolizumab in combination with chemotherapy in…NCT06008093·Beverly Hills, California and 46 others

RecruitingSafety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP LossThis is a first in human study of TNG456 alone and in combination with abemaciclib in patients with advanced or metastatic solid tumors known to have an MTAP loss.NCT06810544·Scottsdale, Arizona and 14 others

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