Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247)

You may be eligible if

• Age greater than or equal to 18
• Histologically or cytologically confirmed non-small-cell lung cancer (NSCLC)
• At least one brain metastasis diagnosed within 30 days of randomization
• Brain metastases must not have been previously treated with WBRT or radiosurgery
• No more than 2 sites of extracranial metastases
• May have received prior radiation therapy to the primary tumor and/or systemic metastatic sites
• Meets protocol requirements for specified laboratory values.
• Written informed consent and cooperation of patient
• Appropriate use of effective contraception if of childbearing potential.
• Karnofsky Performance Status KPS greater than 70
• Score less than 2 on all criteria of the Comprehensive Neurological Outcome Scale (CNOS)