Leukemia Clinical Trials in Detroit

Showing 801-820 of 1,440 trials

An Algorithmic Approach to Ventilator Withdrawal at the End of Life

NCT03121391

The proposed study is an important, under-investigated area of ICU care for terminally ill patients undergoing terminal ventilator withdrawal. The proposed research has relevance to public health because an algorithmic approach to the ventilator withdrawal process will enhance clinicians' ability to conduct the process while assuring patient comfort, using opioids and/or benzodiazepines effectively.

Critical CarePalliative Care

Wayne State University165 participantsStarted Apr 2017

Detroit, Michigan, United States • Detroit, Michigan, United States • Detroit, Michigan, United States +2 more locations

COMPLETEDPhase 2< 1 mile

MK-3475 as Maintenance Therapy in Extensive Stage SCLC

NCT02359019

This phase II trial studies how well pembrolizumab works in treating patients with extensive stage small cell lung cancer after completion of combination chemotherapy. Pembrolizumab may be effective in controlling small cell lung cancer for a longer period of time in patients with responsive or stable disease after completion of combination chemotherapy.

Extensive Stage Small Cell Lung Carcinoma

Barbara Ann Karmanos Cancer Institute45 participantsStarted Feb 2015

Chicago, Illinois, United States • Ann Arbor, Michigan, United States • Detroit, Michigan, United States +2 more locations

An Algorithmic Approach to Ventilator Withdrawal at the End of Life

MK-3475 as Maintenance Therapy in Extensive Stage SCLC

Leukemia Trials in Other Cities

A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)

Docetaxel + Plinabulin Compared to Docetaxel + Placebo in Patients With Advanced NSCLC

Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)

Stereotactic Body Radiotherapy Versus Conventional Radiotherapy in Medically-Inoperable Non-Small Lung Cancer Patients

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

A Study of APTO-253 in Patients With Relapsed or Refractory AML or MDS

Studying the Treatment Effect of Pirfenidone in Chronic Lung Allograft Dysfunction (STOP-CLAD)

Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer

Study of Biomarkers in Blood and Bone Marrow Samples From Patients With Previously Untreated Chronic Lymphocytic Leukemia

A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

Safety, PD & Efficacy of MT-3724 for the Treatment of Patients With Relapsed or Refractory DLBCL

Phase I/II Study of PDR001 in Patients With Advanced Malignancies

P3 (Prepared, Protected, emPowered)

Predictive Assay for Decision Making in Adjuvant Therapy

REGN2810 (Anti-PD-1 Antibody), Platinum-based Doublet Chemotherapy, and Ipilimumab (Anti-CTLA-4 Antibody) Versus Pembrolizumab Monotherapy in Patients With Lung Cancer

Other Conditions in Detroit