Kidney Disease Clinical Trials

Showing 361-380 of 3,346 trials

everlinQ endoAVF Post Market Study

NCT02682420

Prospective, multi-center study to evaluate the everlinQ endoAVF System when used to create an endovascular arteriovenous fistula (endoAVF) for patients who require vascular access for hemodialysis.

Chronic Kidney Disease

C. R. Bard100 participantsStarted Sep 2016

Vancouver, British Columbia, Canada • Dresden, Germany • Düsseldorf, Germany +8 more locations

COMPLETEDPhase 1

An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function

NCT06962774

This a phase 1, open label, single dose, parallel cohort study to determine the pharmacokinetics (PK) of study drug (ESK-001) in healthy volunteer participants, and participants with mild, moderate, and severe renal impairment.

Renal Impairment

Alumis Inc16 participantsStarted Apr 2025

Miami, Florida, United States • Miami Lakes, Florida, United States • Miami Lakes, Florida, United States +1 more locations

COMPLETEDPhase 4

Simulect Versus ATG in Sensitized Renal Transplant Patient

NCT02377193

Induction therapy by either T-cell depleting polyclonal antibodies such as anti-thymocyte globulins (ATG) or non-depleting anti-interleukine 2 receptor monoclonal antibodies (anti-CD25 moAb: basiliximab or daclizumab) are used to prevent acute rejection, especially in highly sensitized patients. Both induction therapy regimens have a different tolerance profile. Infections and haematological side-effects are more frequently reported in patients receiving ATG. The aim of the pilot study is to evaluate ATG and basiliximab induction therapy in de novo sensitized kidney-transplant patients (incompatible grafts rate ≥ 50%) without donor specific antibodies (DSAs) detected by Luminex.

Renal Transplant Rejection

University Hospital, Toulouse60 participantsStarted Sep 2013

Toulouse, France, France

everlinQ endoAVF Post Market Study

An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function

Simulect Versus ATG in Sensitized Renal Transplant Patient

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Piflufolastat F 18 PET/CT in Patients With Suspected, or at High Risk for Metastatic ccRCC

Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients

Novel Desensitization Kidney Transplantation

Incidence of HANA Conditions in HIV-infected Individuals

A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease

Autologous Dendritic Cell as Adjunct Therapy for Diabetic Kidney Disease

Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

Left Atrial Appendage Occlusion in Dialysis Patients With Atrial Fibrillation: A Multicentre Pilot Study

Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)

Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates

A Study to Investigate the Pharmacokinetics, Safety and Tolerability of AZD5462 in Participants With Renal Impairment

Pembrolizumab Plus Lenvatinib for First-line Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61)

Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery

Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease

A Prospective, Multicenter, Randomized, Blinded, Sham-controlled, Feasibility Study of Renal Denervation in Patients With Chronic Heart Failure