Hypertension Clinical Trials

Showing 2421-2440 of 3,009 trials

Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure

NCT01371370

* Obesity is a major risk factor for premature arterial abnormalities including high blood pressure and increased stiffness. Previous studies have shown that weight loss via lifestyle modifications is associated with a decrease in large artery (aorta) stiffness. However, along with decreases in fat mass, hypocaloric diet reduces muscle mass. Low-intensity resistance exercise training (LIRET) results in similar increases in muscle mass and strength than those observed after high-intensity resistance exercise. * The investigators hypothesis is that weight loss via diet combined with LIRET would additively reduce arterial stiffness and blood pressure (BP) in obese women. The investigators also hypothesize that the improved arterial function with weight loss would be associated with beneficial changes in the main mechanisms involved in BP regulation.

ObesityPre-hypertensionHypertension

Florida State University41 participantsStarted Dec 2010

Tallahassee, Florida, United States

COMPLETEDPhase 2

AL-54478 Proof of Concept Study

NCT01318252

The purpose of this study is to assess the safety and efficacy of AL-54478 0.005% compared with Latanoprost 0.005% and AL-54478 Vehicle in patients with open-angle glaucoma or ocular hypertension.

Open-angle Glaucoma (OAG)Ocular Hypertension (OHT)

Alcon Research64 participantsStarted Jun 2011

UNKNOWNPhase 2/3

Clinical Value of Noninvasive Intracranial Pressure Measurement

NCT02130219

The aim of the study is to evaluate accuracy and precision of non-invasive intracranial pressure measurement device (Vittamed 205) for selected patients compared with cerebrospinal fluid pressure measured during lumbar puncture

Intracranial Hypertension

Lithuanian University of Health Sciences45 participantsStarted Jun 2013

Kaunas, Lithuania

Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure

AL-54478 Proof of Concept Study

Clinical Value of Noninvasive Intracranial Pressure Measurement

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Telmisartan Plus Hydrochlorothiazide in Subjects With Mild-to-moderate Hypertension Who Failed to Respond to Telmisartan Monotherapy

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Efficacy and Safety Study of YH16410 Versus Rosuvastatin and Telmisartan Monotherapies in Patients With Hypertension and Hyperlipidemia

Phase 4 Study to Assess the Effect of Bisoprolol on Glycemic Level in Type II Diabetic Subjects With Suboptimal Blood Pressure Control