Hypertension Clinical Trials in Philadelphia

Showing 81-100 of 283 trials

Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso

NCT03950739

This was a Phase 1b safety and tolerability single-sequence study in which PAH subjects on a stable regimen of Tyvaso switched to a corresponding dose of TreT.

Pulmonary Arterial Hypertension

United Therapeutics51 participantsStarted Sep 2019

Birmingham, Alabama, United States • Los Angeles, California, United States • Jacksonville, Florida, United States +13 more locations

COMPLETEDPhase 3< 1 mile

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

NCT04576988

The objectives of this study are to evaluate the efficacy and safety of sotatercept (MK-7962) treatment (plus background pulmonary arterial hypertension (PAH) therapy) versus placebo (plus background PAH therapy) at 24 weeks in adults with PAH. The primary hypothesis of the study is that the participants receiving sotatercept will have improved 6-minute walk distance (6MWD) at 24 weeks compared to participants receiving placebo.

Pulmonary Arterial Hypertension

Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA324 participantsStarted Jan 2021

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +117 more locations

Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

Hypertension Trials in Other Cities

A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Dissemination of the Cardiovascular Risk Service

A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment

Diuretic Comparison Project

Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension

A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)

A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary Hypertension

Postpartum Weight Loss for Women at Elevated Cardiovascular Risk

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

A Study of CIN-107 in Patients With Uncontrolled Hypertension

A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag

Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAH

DE-117 Spectrum 5 Study

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH.

A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)

Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension (IMPAHCT-FUL)

Rivet PVS Therapy in Group 2 PH-HFpEF

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension

Other Conditions in Philadelphia