COPD Clinical Trials

Showing 281-300 of 1,501 trials

Follow-up-study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers

NCT02522026

Between 2012 and 2014, a cohort of 90 COPD subjects of disease severity grades GOLD I-IV as well as 60 healthy control subjects (30 smokers and 30 non-smokers) have been examined regarding different clinical and blood/ sputum derived biomarkers at the investigators' research center. This observation study will follow-up/re-examine all available subjects regarding disease course and treatment changes after 3 years (+/-6 months) for the investigation of ncRNA/ transcriptome biomarkers for their potential to indicate disease progression. In addition, biobanking of respective biosamples for potential future COPD biomarker research will be conducted.

Chronic Obstructive Pulmonary Disease

Fraunhofer-Institute of Toxicology and Experimental Medicine116 participantsStarted Aug 2015

Hanover, Germany

COMPLETEDNA

Advancing Understanding of Transportation Options

NCT04141891

This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers. This multi-site trial will (1) test the driving decision aid (DDA) in improving decision making and quality (knowledge, decision conflict, values concordance and behavior intent); and (2) determine its effects on specific subpopulations of older drivers (stratified for cognitive function, decisional capacity, and attitudinally readiness for a mobility transition). The overarching hypotheses are that the DDA will help older adults make high-quality decisions, which will mitigate the negative psychosocial impacts of driving reduction, and that optimal DDA use will target certain populations and settings.

Diabetic RetinopathyMacular DegenerationGlaucoma+29 more

University of Colorado, Denver529 participantsStarted Dec 2019

La Jolla, California, United States • Aurora, Colorado, United States • Indianapolis, Indiana, United States

Follow-up-study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers

Advancing Understanding of Transportation Options

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