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Clareo Health | COPD Clinical Trials in Houston | 164 Studies

Clinical Trials COPDHouston

COPD Clinical Trials in Houston

Find 164 clinical trials for copd near Houston, Texas. Connect with research centers in your area.

All COPD trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 164 trials

CompletedTiotropium / Respimat One-Year StudyTo evaluate the long term effects of treatment with two doses of Tiotropium delivered by the Respimat inhaler in patients with COPD.NCT00168831·Birmingham, Alabama and 75 others

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Data from ClinicalTrials.govTerms

Active not recruitingEvaluation of the Safety and Efficacy of TLD in Patients with COPDThe purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.NCT03639051·Birmingham, Alabama and 32 others

CompletedClinical Study of Ensifentrine-Glycopyrrolate (MK-5884A/RPL554) Fixed-dose Combination Dose Ranging in Participants With COPD (MK-5884A-029/RPL554-CO-212)This study will assess the safety and efficacy of fixed dose combinations of ensifentrine with two different glycopyrrolate dose levels compared to placebo and to the individual…NCT07016412·Dothan, Alabama and 56 others

CompletedPivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 InflammationPrimary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured…NCT04456673·Cullman, Alabama and 333 others

CompletedDetermine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPDThe purpose of this study is to assess the bronchodilator effect and safety of multiple daily doses of arformoterol administered for 12 weeks as maintenance treatment in patients…NCT00064402·Jasper, Alabama and 64 others

CompletedComparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to Severe Exacerbations in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease.The overall objective is to assess the effect of once daily tiotropium + olodaterol fixed dose combination compared to 5 µg tiotropium (both delivered with the Respimat® inhaler)…NCT02296138·Andalusia, Alabama and 817 others

RecruitingDepemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 InflammationDepemokimab is being developed as a treatment for individuals with moderate to severe COPD.NCT06959095·Bakersfield, California and 280 others

CompletedA Study of Exercise Endurance and Lung Hyperinflation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)This study evaluated the effect of inhaled aclidinium bromide on exercise endurance and in reducing resting and dynamic lung hyperinflation in patients with moderate to severe…NCT00500318·Jasper, Alabama and 51 others

CompletedEfficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPDThis is a trial of 12 weeks of treatment with nebulized SUN-101 using an Investigational eFlow® Closed System (CS) nebulizer in subjects with chronic obstructive pulmonary disease…NCT02347761·Anniston, Alabama and 43 others

CompletedA Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients.The objective of this study is to evaluate the efficacy and safety of 12 weeks treatment with tiotropium HandiHaler 18 micrograms (mcg) daily compared to Combivent Metered Dose…NCT00359788·Birmingham, Alabama and 30 others

CompletedAn Efficacy and Safety Study to Compare Three Doses of BEA 2180 BR to Tiotropium and Placebo in the Respimat Inhaler.The primary objective of this study is to compare the bronchodilator efficacy of three doses (50 µg, 100 µg and 200 µg) of BEA 2180 delivered by the Respimat® once daily to…NCT00528996·Jasper, Alabama and 177 others

CompletedA Comparison of Symbicort® pMDI 2 x 160/4.5 μg Bid and 2 x 80/4.5 μg Bid With Formoterol Turbuhaler® 2 x 4.5 μg Bid and Placebo in Patients With COPDThe purpose of this study is to compare Symbicort in a pressurized metered-dose inhaler (pMDI) with formoterol and placebo in the long-term maintenance treatment of patients with…NCT00206167·Birmingham, Alabama and 215 others

CompletedA Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)The study evaluates the efficacy of fluticasone furoate/umeclidinium bromide/vilanterol (FF/UMEC/VI) to reduce the annual rate of moderate and severe exacerbations compared with…NCT02164513·Athens, Alabama and 997 others

CompletedDose Finding Study in COPDThe primary objective of this study is to determine the optimum dose of BEA 2180 BR inhalation solut ion delivered by the Respimat ? inhaler once daily for four weeks in patients…NCT00122434·Birmingham, Alabama and 42 others

CompletedLongitudinal Follow up to Assess Biomarkers Predictive of Emphysema Progression in Patients With COPD (Chronic Obstructive Pulmonary Disease)The study will include 60 healthy subjects (ex-smoker without any airflow limitation), 125 COPD GOLD (global initiative for chronic obstructive lung disease) I , 125 COPD GOLD II…NCT02719184·Birmingham, Alabama and 50 others

CompletedVibration Response Imaging in Chronic Obstructive Pulmonary Disease and AsthmaObstructive lung disease is usually a differential diagnostic consideration when a patient presents with breathlessness or cough.NCT00542282·Houston, Texas

Active not recruitingFrespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPDResearchers are looking for ways to treat pulmonary hypertension (PH) caused by chronic obstructive pulmonary disease (COPD).NCT05612035·San Francisco, California and 84 others

TerminatedA 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)The purpose of this study is to evaluate the efficacy and the safety of two doses of CHF6001 (Tanimilast) as add-on to maintenance triple therapy in the target patient population.NCT04636814·Andalusia, Alabama and 459 others

CompletedA Culturally Sensitive Values-Guided Aid for End of Life Decision-MakingThe goal of this research agenda is to improve the quality of end-of-life care by explicitly identifying values that will guide the decision-making process, with a particular…NCT00122135·Houston, Texas

RecruitingA Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very…NCT06878261·Birmingham, Alabama and 283 others

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