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Clareo Health | COPD Clinical Trials in Philadelphia | 185 Studies

Clinical Trials COPDPhiladelphia

COPD Clinical Trials in Philadelphia

Find 185 clinical trials for copd near Philadelphia, Pennsylvania. Connect with research centers in your area.

All COPD trials nationwide All trials in Philadelphia

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 185 trials

CompletedPhase IV O2 Consumption Study in COPD Patients.A Phase IV study evaluating changes in oxygen consumption and cardiac function in Subjects with Chronic obstructive pulmonary disease (COPD) with resting hyperinflation after…NCT02533505·Hartford, Connecticut and 4 others Active not recruitingEvaluation of the Safety and Efficacy of TLD in Patients with COPDThe purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.NCT03639051·Birmingham, Alabama and 32 others

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Data from ClinicalTrials.govTerms

CompletedLung Tissue Research ConsortiumThe LTRC will facilitate histopathological research of pulmonary diseases by collecting lung tissues from donors and preparing and distributing collections of tissue specimens to…NCT02988388·Ann Arbor, Michigan and 3 others

TerminatedA Prospective, Cohort Study of Hyperpolarized 3He MRI in Chronic Obstructive Pulmonary DiseaseThe purpose of this study is to determine the MRI characteristics of Chronic Obstructive Pulmonary Disease subjects both at baseline and yearly for a period of 5 years, and to…NCT02734368·Philadelphia, Pennsylvania

CompletedDetermine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPDThe purpose of this study is to assess the bronchodilator effect and safety of multiple daily doses of arformoterol administered for 12 weeks as maintenance treatment in patients…NCT00064402·Jasper, Alabama and 64 others

CompletedComparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to Severe Exacerbations in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease.The overall objective is to assess the effect of once daily tiotropium + olodaterol fixed dose combination compared to 5 µg tiotropium (both delivered with the Respimat® inhaler)…NCT02296138·Andalusia, Alabama and 817 others

CompletedA Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPDThe primary objective of this study is to compare the effects of orally inhaled tiotropium + olodaterol fixed dose combination (2.5/5 µg; 5/5 µg) with placebo on exercise…NCT01525615·Torrance, California and 59 others

CompletedUS Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema StudyThe purpose of this study it to evaluate the efficacy and safety of the 20 mL BLVR System in patients with advanced upper lobe predominant emphysema.NCT00515164·Phoenix, Arizona and 7 others

CompletedA Study of Exercise Endurance and Lung Hyperinflation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)This study evaluated the effect of inhaled aclidinium bromide on exercise endurance and in reducing resting and dynamic lung hyperinflation in patients with moderate to severe…NCT00500318·Jasper, Alabama and 51 others

CompletedAn Efficacy and Safety Study to Compare Three Doses of BEA 2180 BR to Tiotropium and Placebo in the Respimat Inhaler.The primary objective of this study is to compare the bronchodilator efficacy of three doses (50 µg, 100 µg and 200 µg) of BEA 2180 delivered by the Respimat® once daily to…NCT00528996·Jasper, Alabama and 177 others

CompletedA Comparison of Symbicort® pMDI 2 x 160/4.5 μg Bid and 2 x 80/4.5 μg Bid With Formoterol Turbuhaler® 2 x 4.5 μg Bid and Placebo in Patients With COPDThe purpose of this study is to compare Symbicort in a pressurized metered-dose inhaler (pMDI) with formoterol and placebo in the long-term maintenance treatment of patients with…NCT00206167·Birmingham, Alabama and 215 others

CompletedA Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)The study evaluates the efficacy of fluticasone furoate/umeclidinium bromide/vilanterol (FF/UMEC/VI) to reduce the annual rate of moderate and severe exacerbations compared with…NCT02164513·Athens, Alabama and 997 others

CompletedSocial Incentives to Increase MobilityThis study aims to assess the effectiveness of a social incentive-based gamification intervention to increase physical activity in the 3 months after hospital discharge.NCT03321279·Philadelphia, Pennsylvania

CompletedA Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a Next-Generation Propellant in Participants 40 to 80 Years of Age With COPDThe purpose of this study is to demonstrate that the lung function effect from orally inhaled BGF delivered via HFO propellant is equivalent to the lung function effect from…NCT06075095·Sheffield, Alabama and 86 others

CompletedDose Finding Study in COPDThe primary objective of this study is to determine the optimum dose of BEA 2180 BR inhalation solut ion delivered by the Respimat ? inhaler once daily for four weeks in patients…NCT00122434·Birmingham, Alabama and 42 others

RecruitingClosed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the HospitalThe trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized…NCT07222410·Birmingham, Alabama and 3 others

CompletedLongitudinal Follow up to Assess Biomarkers Predictive of Emphysema Progression in Patients With COPD (Chronic Obstructive Pulmonary Disease)The study will include 60 healthy subjects (ex-smoker without any airflow limitation), 125 COPD GOLD (global initiative for chronic obstructive lung disease) I , 125 COPD GOLD II…NCT02719184·Birmingham, Alabama and 50 others

CompletedEfficacy and Safety Study of QVA149 in COPD PatientsThe purpose of this study is to demonstrate that the efficacy of the combination product QVA149 is similar to the efficacy of the combination product umeclidinium/vilanterol on a…NCT02487446·Andalusia, Alabama and 57 others

CompletedSymbicort in Airway Predominant Chronic Obstructive Pulmonary Disease (COPD)The main objective of the study is to see if using anti-inflammatory to patients with airway disease chronic obstructive pulmonary disease (COPD) phenotype will be more effective…NCT01253473·Birmingham, Alabama and 6 others

Active not recruitingFrespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPDResearchers are looking for ways to treat pulmonary hypertension (PH) caused by chronic obstructive pulmonary disease (COPD).NCT05612035·San Francisco, California and 84 others

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