COPD Clinical Trials in New York

Showing 21-40 of 134 trials

Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management

NCT06634810

The Icahn School of Medicine at Mount Sinai will conduct a randomized controlled trial of a self-management support intervention for predominantly minoritized and low-income adults with chronic obstructive pulmonary disease (COPD). The trial will focus on comprehensive screening and targeted management of barriers to COPD control, incorporating home-based pulmonary rehabilitation and oral steroid and antibiotic prescribing for pre-emptive treatment of COPD exacerbations. The research team will compare this intervention with an attention control group to evaluate the effects on medication adherence, COPD symptoms, inhaler technique, physical activity and exercise capacity at 6 months, and at 12 months to examine sustainability of treatment effects. The research team will also examine hospitalizations and emergency department visits at 12 months. The study will recruit 300 participants from the Mount Sinai Health System in Manhattan, Queens, and Brooklyn, ensuring diverse representation. Health coaches from the VNS Health will deliver the intervention, guided by a detailed training manual. Weekly conference calls will address logistical and protocol-related issues.

Chronic Obstructive Pulmonary Disease

Icahn School of Medicine at Mount Sinai300 participantsStarted Sep 2024

New York, New York, United States

RECRUITING< 1 mile

SPIROMICS Study of Early COPD Progression (SOURCE)

NCT05033990

This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: * To use CT scan imaging to identify which smokers will develop COPD. * To identify biomarkers predictive of smokers that will develop COPD. * To determine if sputum (phlegm) can be analyzed to predict which smokers will develop COPD. Procedures (methods): All participants will undergo study related questionnaires assessing medical history, smoke exposure and use, medication use, social and behavioral health, pulmonary symptoms, food frequency, and will provide nasal swab, blood, stool, and urine samples, pulmonary function testing to determine function, sputum induction to provide a sputum sample for airway biospecimen analysis, and CT imaging of the lungs.

COPD, Early-Onset

University of Massachusetts, Worcester1,000 participantsStarted Sep 2021

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Los Angeles, California, United States +11 more locations

Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management

SPIROMICS Study of Early COPD Progression (SOURCE)

COPD Trials in Other Cities

Defective FGFR2 Signaling in the Small Airway Basal Progenitor Cells in COPD

Observational Study of Obstructive Lung Disease (NOVELTY)

Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary

A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)

A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs

High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis

A Phase 2 Study of MP-376 to Prevent Acute Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Patients

Impairments That Affect Correct Inhaler Use in COPD

Changing the Paradigm of In-Hospital Cardiopulmonary Resuscitation

Music During Pulmonary Rehabilitation for Patients With COPD

Exacerbations and Their Outcomes International (EXACOS International)

Evaluation of VQm PHM on Pulmonary Health Parameters for ICU

Other Conditions in New York