COPD Clinical Trials in Chicago

Showing 41-60 of 125 trials

Feasibility of At-Home Handheld Spirometry

NCT03284203

The investigators' central hypotheses predict that the handheld spirometry device will be feasible for inpatient and at-home use, and is equally efficacious at determining lung function when compared to traditional, bedside spirometry measurements. To test these hypotheses, the investigators propose the following specific aims: Specific Aim 1: Determine the correlation of SpiroPD handheld spirometry measurements with bedside Koko spirometry lung function. Hypothesis: Correlation between the two lung function tests will be substantial for both hospitalized and ambulatory patients. Specific Aim 2: To determine the feasibility, adherence, and preliminary management efficacy of home SpiroPD testing. Hypotheses: (1) Patients will demonstrate substantial adherence to daily home spirometry testing; (2) medication adherence will increase significantly in patients who are adherent to daily home spirometry testing; (3) acute care utilization will decrease significant in adherent patients.

COPD

University of Chicago8 participantsStarted Sep 2017

Chicago, Illinois, United States

COMPLETED2.2 miles

Respiratory Infection Monitoring

NCT04362631

This study will monitor physical bio-markers such as heart rate, respiratory rate, and temperature to detect potential respiratory infections.

Chronic Obstructive Pulmonary Disease (COPD)

Northwestern University42 participantsStarted Apr 2020

Chicago, Illinois, United States

TERMINATEDNA2.2 miles

Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD

NCT03255057

This study evaluates the safety and efficacy of using the Hemolung RAS to provide low-flow extracorporeal carbon dioxide removal (ECCO2R) as an alternative or adjunct to invasive mechanical ventilation for patients who require respiratory support due to an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). It is hypothesized that the Hemolung RAS can be safely used to avoid or reduce time on invasive mechanical ventilation compared to COPD patients treated with standard-of-care mechanical ventilation alone. Eligible patients will be randomized to receive lung support with either the Hemolung RAS plus standard-of-care mechanical ventilation, or standard-of-care mechanical ventilation alone.

Acute Exacerbation of COPD

Alung Technologies113 participantsStarted Feb 2018

Sacramento, California, United States • Denver, Colorado, United States • Newark, Delaware, United States +29 more locations

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Feasibility of At-Home Handheld Spirometry

Respiratory Infection Monitoring

Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD

COPD Trials in Other Cities

At Home Spirometry and Video Module Education for COPD Patients

A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary Disease

An Educational Intervention to Improve Disease Management Knowledge of Hospitalized Patients With COPD

Effectiveness of Interventions to Teach Respiratory Inhaler Technique (E-TRaIN)

A Technology Assisted Care Transition Intervention for Veterans With CHF or COPD

Assessment of Utility of accelerateIQ in the Care of Patients Participating in a Pulmonary Rehabilitation Program

Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

Randomized Evaluation of Default Access to Palliative Services

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

A 42-day Parallel Group Safety Study of Revefenacin and Formoterol, Administered in Sequence and as a Combination, in Participants With COPD

Clinical Endpoint Bioequivalence Study of Test and Reference Inhalation Products in Patients With COPD With Device Robustness

Two-Part Dose-Confirming Study of Pulsed Inhaled Nitric Oxide in Subjects With WHO Group 3 Pulmonary Hypertension Associated With COPD

Improving Quality by Maintaining Accurate Problems in the EHR

An Efficacy and Safety Profile of Inhaled TV48108 in Healthy Volunteers and COPD Patients

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2)

Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease

Other Conditions in Chicago