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Clareo Health | Brain Cancer Clinical Trials | 951 Studies Recruiting

Clinical TrialsBrain Cancer

Brain Cancer Clinical Trials

Browse 951 clinical trials for brain cancer. Find studies that match your criteria and connect with research centers.

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Showing 61-80 of 951 trials

CompletedA Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) AmplificationThis study seeks to determine whether the addition of ABT-414 to concomitant radiotherapy and temozolomide (TMZ) followed by combination of ABT-414 with adjuvant TMZ prolongs…NCT02573324·Phoenix, Arizona and 211 others

Related Searches

glioblastomatrials gliomatrials brain tumortrials

Data from ClinicalTrials.govTerms

Active not recruitingA Study of Abemaciclib in Recurrent GlioblastomaThis research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM). The following intervention will be used in this study: -AbemaciclibNCT02981940·Los Angeles, California and 6 others

RecruitingA Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade GliomaThis is an open-label, multicenter dose-escalation study to be followed by a dose expansion to define the optimal dose of GLIX1 as monotherapy by reviewing safety and…NCT07464925·Tampa, Florida and 2 others

CompletedGene Therapy in Treating Patients With Primary Brain TumorsRATIONALE: Inserting the gene for herpes virus into a person's cells may improve the body's ability to fight cancer or make the cancer more sensitive to chemotherapy using…NCT00002824·Philadelphia, Pennsylvania

Active not recruitingA Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma MultiformeThe current design provides a window to analyze the impact of the ACT001+Pembrolizumab combination on the tumor microenvironment and disease outcomes.NCT05053880·Houston, Texas

CompletedGliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4The goal of this observational study is to learn whether an artificial intelligence system called GliomaAI-Astro4 can help detect a specific molecular type of brain tumour called…NCT07673679·Mumbai

CompletedRadiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00099125·Phoenix, Arizona and 117 others

TerminatedPhase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or GliosarcomaThe goal of this clinical research study is to find the highest tolerable dose of sorafenib that can be given in combination with temozolomide.NCT00734526·Houston, Texas

CompletedRadiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain TumorsRATIONALE: Monoclonal antibodies can locate tumor cells and deliver radioactive tumor-killing substances such as radioactive iodine to them without harming normal cells.NCT00003478·Durham, North Carolina

CompletedRadiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain TumorsRATIONALE: Monoclonal antibodies can locate tumor cells and deliver tumor-killing substances, such as radioactive iodine, to them without harming normal cells.NCT00003484·Durham, North Carolina

CompletedCellular Adoptive Immunotherapy in Treating Patients With Glioblastoma MultiformeRATIONALE: Biological therapies, such as cellular adoptive immunotherapy, may stimulate the immune system in different ways and stop tumor cells from growing.NCT00331526·Newport Beach, California

CompletedABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS TumorsThis phase I trial is studying the side effects and best dose of ABT-888 when given in combination with temozolomide in treating young patients with recurrent or refractory CNS…NCT00946335·Memphis, Tennessee

CompletedRadiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00006353·Calgary, Alberta and 15 others

TerminatedPhase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) PatientsThe purpose of this study is to determine whether the addition of an investigational medication, axitinib, to radiation therapy will improve the outcome of treatment in patients…NCT01508117·Cincinnati, Ohio

CompletedMRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma MultiformeThis pilot clinical trial studies magnetic resonance imaging (MRI)-guided laser surgery (MLA) and doxorubicin hydrochloride in treating patients with recurrent glioblastoma…NCT01851733·St Louis, Missouri

TerminatedTesting Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain TumorsRecent advances in technology have allowed for the detection of cell-free DNA (cfDNA). cfDNA is tumor DNA that can be found in the fluid that surrounds the brain and spinal cord…NCT05934630·Los Angeles, California and 9 others

RecruitingPLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN AmplificationsBackground: About 90,000 new cases of brain and spinal cord tumors are diagnosed annually in the United States.NCT06161519·Bethesda, Maryland

CompletedAvastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and GliosarcomasPrimary objective- To determine efficacy of Avastin, 10 mg/kg every other week, in combination with standard 5-day temozolomide in terms of response rate.NCT00612339·Durham, North Carolina

CompletedNBI-3001 Followed by Surgery in Treating Patients With Recurrent Glioblastoma MultiformeRATIONALE: NBI-3001 may be able to locate cancer cells and stop them from growing. This may be an effective treatment for glioblastoma multiforme.NCT00014677·La Jolla, California and 3 others

CompletedPhase 1b Study PVSRIPO for Recurrent Malignant Glioma in ChildrenThe purpose of the study is to confirm the safety of the selected dose and potential toxicity of oncolytic poliovirus (PV) immunotherapy with PVSRIPO for pediatric patients with…NCT03043391·Durham, North Carolina

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