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Clinical Trials Bipolar DisorderChicago

Bipolar Disorder Clinical Trials in Chicago

Find 80 clinical trials for bipolar disorder near Chicago, Illinois. Connect with research centers in your area.

All Bipolar Disorder trials nationwide All trials in Chicago

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 80 trials

CompletedLithium Therapy: Understanding Mothers, Metabolism and MoodLithium, the gold standard for treatment of Bipolar Disorder (BD) and a common augmentation to medication therapy for Major Depression, is commonly continued in pregnancy due to…NCT02490241·Chicago, Illinois TerminatedEfficacy and Safety of Ramelteon Sublingual in Adult Patients With Acute Depressive Episodes Associated With Bipolar I DisorderThe purpose of this study is to determine the efficacy and safety of Ramelteon, once daily (QD), sublingual (SL), in adult participants with acute depressive episodes associated…NCT01467700·Birmingham, Alabama and 160 others

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Data from ClinicalTrials.govTerms

CompletedUnderstanding How Cognitive Remediation WorksThis study is aimed at evaluating whether the computer-based cognitive exercises in the Thinking Skills for Work (TSW) program are critical to improving work and cognitive…NCT01683539·Chicago, Illinois and 1 other

CompletedDifferential Responses to Drugs and Sweet TastesYoung adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders…NCT03810703·Chicago, Illinois and 1 other

CompletedLumateperone Monotherapy for the Treatment of Bipolar Depression Conducted GloballyThe study will evaluate the efficacy and safety of ITI-007 in a randomized, double-blind, parallel-group, placebo-controlled, multi-center study in patients diagnosed with Bipolar…NCT03249376·Birmingham, Alabama and 46 others

CompletedSafety and Efficacy of Cariprazine for ManiaThe objective of this study is to evaluate the efficacy, safety, and tolerability of cariprazine monotherapy versus placebo for the treatment of acute manic or mixed episodes…NCT01058096·Long Beach, California and 27 others

CompletedDexmedetomidine in the Treatment of Agitation Associated With Bipolar DisorderThis is a definitive study to support the safety and efficacy evaluation of BXCL501 for the acute treatment of agitation in bipolar disorder.NCT04276883·Little Rock, Arkansas and 14 others

Active not recruitingStudy of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in AdultsThe goal of this clinical trial is to learn if ABX-002 added to participants' existing treatment(s) can improve clinical symptoms of depression and to learn about potential…NCT06869187·Walnut Creek, California and 13 others

CompletedBipolar and Schizophrenia Consortium for Parsing Intermediate PhenotypesBriefly, this multisite study is designed to identify endophenotypes (i.e., heritable biomarkers) associated with either schizophrenia or bipolar disorder alone, or both together.NCT00666432·Hartford, Connecticut and 5 others

CompletedClinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar DepressionThe study will evaluate the efficacy and safety of ITI-007 adjunctive to lithium or valproate in a randomized, double-blind, parallel-group, placebo-controlled, multi-center study…NCT02600507·Rogers, Arkansas and 70 others

CompletedTelemedicine for Women With Anhedonia in Bipolar and Unipolar DisorderAnhedonia, characterized as (a) the diminished motivation to participate in activities, and/or (b) diminished enjoyment of a pleasurable activity are common symptoms among women…NCT02494050·Chicago, Illinois

RecruitingA Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II DisorderBipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States.NCT06696755·Huntsville, Alabama and 32 others

CompletedA Mobile Behavioral Monitoring Intervention for Bipolar DisorderThis study will develop and pilot a smartphone intervention, LiveWell, to enhance patient self-management of bipolar disorder and facilitate more efficient, timely care delivery…NCT02405117·Chicago, Illinois

CompletedEfficacy and Safety of Seroquel Plus Mood Stabilizer in the Maintenance of Bipolar I DisorderThe purpose of this study is to determine whether quetiapine when used as adjunct to lithium or divalproex is safe and effective in the maintenance treatment of adult patients…NCT00081380·Birmingham, Alabama and 93 others

CompletedThinking Skills for Work in Severe Mental IllnessThe purpose of this study is help people with serious mental illness and receiving vocational rehabilitation get and keep the job they want by improving their thinking skills…NCT01926613·Chicago, Illinois and 1 other

CompletedStudy to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I DisorderThis study will evaluate the effect of ALKS 3831 compared to olanzapine on body weight in young adults with schizophrenia, schizophreniform, or bipolar I disorder who are early in…NCT03187769·Little Rock, Arkansas and 56 others

CompletedStudy of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression EpisodeThe purpose of this study is to evaluate flexible doses (5-30mg) of aripiprazole versus placebo in patients with bipolar depression.NCT00080314·Tuscaloosa, Alabama and 27 others

CompletedTesting the Ability of JNJ-18038683 to Improve Cognition and Reduce Depressive Symptoms in Stable Bipolar PatientsThe goals of this study are to evaluate the efficacy of JNJ-18038683 in an 8 week trial to ameliorate the cognitive deficit and reduce residual depressive symptoms in 60 stable…NCT02466685·Chicago, Illinois

CompletedThe Assessment of a Weight-Gain Agent for the Treatment of Olanzapine-Associated Anti-Obesity Agent in Patients With Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, and Bipolar I DisorderOlanzapine is currently marketed for the treatment of schizophrenia and acute manic episodes with bipolar 1 disorder.NCT00044187·El Centro, California and 15 others

RecruitingA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderThe purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I DisorderNCT06951698·Bentonville, Arkansas and 73 others

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Clareo Health | Bipolar Disorder Clinical Trials in Chicago | 80 Studies