Clinical Trial of an Anti-Fog Drainage Device for Endoscopic Endonasal Sellar Region Tumor Surgery

Exclusion Criteria

• •Severe nasal anatomical deformity, polyps, or prior nasal surgery preventing device placement
• •Active nasal or systemic infection (WBC \> 10 × 10⁹/L, CRP ≥ 10 mg/L)
• •Known intracranial infection or ongoing CSF leak
• •Coagulopathy (PT \> 14 s or APTT \> 45 s) or anticoagulation that cannot be stopped ≥ 7 days
• •Allergy to silicone or medical-grade plastics
• •Planned combined transcranial or transorbital approach
• •Pregnancy or breastfeeding
• •Psychiatric or cognitive disorder precluding informed consent or follow-up