EGFR-positive cancer defined by a board certified pathologist
Primary or metastatic lesion size \>= 1.5 cm as determined by imaging studies (ultrasonography, mammography, CT or MRI) or physical examination.
Able to give informed consent.
Not currently pregnant or nursing: If female subject must be surgically sterile (has had a documented bilateral oophorectomy and/or documented hysterectomy), post-menopausal (cessation of menses for \> 1 year), non-lactating, or of childbearing potential for whom a urine pregnancy test is negative when taken within the 24 h before administration of 89Zr-DFO-nimotuzumab.
WHO performance status of 0 - 2
Patients naïve to anti-EGFR antibodies treatment.
You may not be if
Unable to tolerate 60 min of PET imaging per session.
