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Image Guided VATS vs. VATS Resection | Clinical Trials | Clareo Health

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RECRUITINGNANCT03623958

Image Guided VATS vs. VATS Resection

To evaluate workflow and outcomes of iVATS and standard VATS for small pulmonary nodules. The outcomes of the patients will be evaluated separately as there will be no direct comparison of the two arm...

Lead sponsor: Brigham and Women's Hospital•1 U.S. locations•View source on ClinicalTrials.gov

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Contacts

Julianne S Barlow

CONTACT

617-525-8704 [email protected]

Sponsors

Lead Sponsor

Brigham and Women's Hospital

This is a prospective phase II clinical study to evaluate iVATS and standard VATS for small pulmonary nodules. We have successfully completed and published a phase I/pilot study with 25 patients demonstrating safety and optimal procedural workflow for combining image-guidance with VATS. This phase II clinical study will further expand upon the safety and feasibility of this procedure. Additionally, this data will be used to design a phase III comparison study between iVATS and standard VATS.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Subject must be 18 years and older
•Subject must be deemed a candidate for the iVATS surgery, by their treating Thoracic Surgeon
•Subject must have nodules/GGO or other abnormal opacity that can be accurately measured in at least one dimension with longest diameter ≤ 20 mm or 2cm
•Subject's lesions that are located in the outer half portion of the lung/lobe.
•Subjects must be evaluated at BWH and/or DFCI Thoracic Surgery outpatient clinics

Exclusion Criteria

•If participant is a pregnant woman or breast feeding they will not be eligible.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 13, 2025Terms

Trial snapshot

StatusRECRUITING

PhaseNA

Enrollment200

Start dateSep 2018

Last updatedNov 13, 2025

Condition

Locations shown

Brigham and Women's Hospital

Boston, Massachusetts

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 13, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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