Efficacy and Safety of BIIB111 for the Treatment of Choroideremia

Exclusion Criteria

• •Have a history of amblyopia in the eligible eye.
• •Have had previous intraocular surgery performed in the study eye within 3 months of Visit 1.
• •Have any other significant ocular or non-ocular disease/disorder which, in the opinion of the investigator, may either put the participants at risk because of participation in the study, or may influence the results of the study, or the participant's ability to participate in the study.
• •Have participated in another research study involving an investigational product in the past 12 weeks or received a gene/cell-based therapy at any time previously.
• •Are unwilling to use barrier contraception methods, or abstain from sexual intercourse, for a period of 3 months, if treated with AAV2-REP1.