REP1 Gene Replacement Therapy for Choroideremia

Exclusion Criteria

• •1. Any female, or a male aged below 18 years.
• •2. An additional cause for sight loss (e.g. amblyopia) in the eye to be treated.
• •3. Any other significant ocular and non-ocular disease or disorder which, in the opinion of the investigator, may put the participants at risk because of participation in the study.
• •4. Inability to take systemic prednisolone for a period of 45 days.
• •5. Unwillingness to use barrier contraception methods for a period of three months following gene therapy surgery.
• •6. Participation in another research study involving an investigational product in the preceding 12 weeks.