BuMA OCT Study(A Comparative Evaluation of the Extent of Neointima Formation at 3 Months After Implantation Using OCT)

Exclusion Criteria

• •Evidence of ongoing acute myocardial infarction in ECG prior to procedure.
• •Left ventricular ejection fraction(LVEF) \<30%.
• •Documented or suspected liver disease (including laboratory evidence of hepatitis).
• •Known renal insufficiency (e.g. estimated glomerular filtration rate(eGFR) \<60 ml/kg/m2 or serum creatinine level of \>2.5 mg/dL, or subject on dialysis).
• •History of bleeding diathesis or coagulopathy.
• •The patient is a recipient of a heart transplant.
• •Known hypersensitivity or contraindication to aspirin, both heparin and bivalirudin, antiplatelet medication specified for use in the study (clopidogrel and ticlopidine), sirolimus or stainless steel.
• •Other medical illness (e.g. cancer, neurological deficiency) or known history of substance abuse (alcohol etc.) as per physician judgment that may cause non-compliance with the protocol or confound the data interpretation or is associated with a limited life expectancy.
• •Pregnant or breastfeeding woman or woman in fertile period not taking adequate contraceptives
• •Severe tortuous, calcified or angulated coronary anatomy of the study vessel that in the opinion of the investigator would result in suboptimal imaging or excessive risk of complication from placement of an OCT catheter
• •Total occlusion or thrombolysis in myocardial infarction(TIMI) flow 0, prior to wire crossing.