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1–20 of 1,469
Unknown
The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients
Exploring the efficacy and safety of oral minocycline combined with antiepileptic drugs in the treatment of drug-resistant epilepsy in NORSE patients, obtaining preliminary…
NCT05958069
·
Xi'an, Shaanxi
Recruiting
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
This is a multicenter, Phase 3, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of clemizole hydrochloride (EPX-100) as adjunctive…
NCT04462770
·
Birmingham, Alabama and 67 others
Not yet recruiting
Levetiracetam Compared to Magnesium Sulfate for Prevention of Eclamptic Seizure
The goal of this study is to compare levetiracetam to magnesium sulfate for the prevention of eclamptic seizures in pregnant persons with severe preeclampsia that are 32 or more…
NCT07220902
·
Omaha, Nebraska
Completed
Bioequivalency Study of Levetiracetam 1g Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Levetiracetam 1000 mg Tablets under fasted conditions
NCT00826722
·
Houston, Texas
Unknown
Evaluating the NeoTree in Malawi and Zimbabwe
Neonatal mortality remains unacceptably high. Globally, the majority of mothers now deliver in health facilities in low resource settings where quality of newborn care is poor.
NCT05127070
·
Lilongwe and 4 others
Completed
To Demonstrate the Relative Bioavailability of Sandoz Inc. and UCB Pharma, Inc (Keppra) 750 mg Levetiracetam Tablets In Healthy Adults Volunteers Under Fasting Conditions
To demonstrate the relative bioavailability of Sandoz Inc. and UCB Pharma, Inc (Keppra) 750 mg Levetiracetam tablets in healthy adult volunteers under fasting conditions.
NCT00946751
Active not recruiting
Cenobamate in Adults With Focal-Onset Seizures
The BLESS Study contributes to filling this information gap by collecting data from the Italian clinical practice and the Compassionate Use Program, to better characterize the…
NCT05859854
·
Bari, Bari and 9 others
Unknown
Impact of SPEAC® System Data on Therapeutic Decisions Related to Convulsive Seizure Patients With a Recent Non-diagnostic EMU Visit
This is an open label, randomized, prospective study of the impact on healthcare utilization of a surface Electromyography (sEMG) based seizure monitoring and alerting system for…
NCT03741205
Completed
Nonconvulsive Seizure Identification on Quantitative EEG by Neuro ICU Nurses
This research is being conducted to determine if Neuroscience intensive care unit (ICU) nurses are able to identify seizures by reviewing quantitative EEG (qEEG) that is running…
NCT02082873
·
Durham, North Carolina
Active not recruiting
A Retrospective Database Study for the Development and Validation of Algorithms for Intracerebral Hemorrhage and Seizures in Alzheimer's Disease
The primary objective of this study is to develop and validate claims-based algorithms to identify intracerebral hemorrhage \>1 cm in diameter, ensuring differentiation from…
NCT07723950
·
Nutley, New Jersey
Recruiting
Augmented Renal Clearance in Neurocritical Care
Stroke, severe brain injury, uncontrolled seizures and brain infections are the most common life-threatening neurological illnesses in the world with an estimated combined annual…
NCT07410624
·
Lexington, Kentucky and 2 others
Recruiting
Antiepileptic Drugs in Elderly Patients
The purpose is to study the population pharmacokinetics, effectiveness and safety of antiepileptic drug (phenytoin, carbamazepine, lamotrigine, levetiracetam, parempanel, etc) in…
NCT05459597
·
Jinan, Shandong
Unknown
Second-Line Treatment Choice for Epilepsy
Most patients are prescribed valproate as their first antiepileptic drug. It is unknown which is the best second-line drug when patients do not become seizure free on valproate.
NCT00208520
·
Zwolle
Completed
Revisiting Survey Investigating Why Patients Are Not Receiving Home Anti-convulsant Medication Prior to Surgery/or Procedure Involving General Anesthesia
Children with seizure disorder face unique challenges during the perioperative period.
NCT01897974
·
Columbus, Ohio
Active not recruiting
Epilepsy Watch After Vascular Events: Frequency, Outcomes, and Risk Markers
This research aims to determine the frequency of seizures in patients following a stroke, identify risk factors associated with post-stroke seizures, and characterize EEG changes…
NCT06922734
·
Maribor
Terminated
Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with…
NCT02090998
·
New Brunswick, New Jersey
Active not recruiting
Trial of Multi-Strain Probiotic Supplementation (Hexbio®) in Malaysian Patients With Drug-Resistant Epilepsy (ProbE)
Probiotics are good, live bacteria and/or yeast, that live in our guts and causes no harm. They help in digestion and overall well-being of our gut system.
NCT07100743
·
Kuala Lumpur
Terminated
Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome
Severe acute alcohol withdrawal syndrome is a potentially life-threatening condition characterized by agitation, confusion, abnormal heart rhythms and seizures.
NCT03586089
·
Toronto, Ontario
Completed
Long Term Effectiveness and Safety Study for RWJ-333369 as Adjunctive Therapy in Korean and Japanese Patients With Partial Onset Seizures
The purpose of this study is to evaluate the long-term safety of RWJ-333369 at doses between 200-800 mg/day in Korean and Japanese patients who have completed the preceding study…
NCT00697918
Completed
eegCap Application in Paediatrics wiTh redUced GCS in REsus
Children frequently present with altered or reduced consciousness levels to emergency departments.
NCT05259891
·
Cork, Munster
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