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1–20 of 1,299
Completed
Multiple Sclerosis Rehabilitation Study
The effects of routine rehabilitation in MS patients versus no rehabilitation.
NCT00202254
Completed
Fatigue in MS: From Invisible to Measurable
Fatigue is one of the most common and burdensome symptoms of MS, but its precise cause remains unknown, and an effective treatment is lacking.
NCT07182903
·
Groningen
Withdrawn
A Cross-Sectional Study of MSDx Complex 1 as a Marker for Active Disease in Multiple Sclerosis
This is a Cross-Sectional Study of MSDx Complex 1 as a Marker for Active Disease in Multiple Sclerosis.
NCT01539395
·
Tucson, Arizona
Recruiting
Impact of TTNS on Bladder Symptoms Among People With MS, A RCT
Background: Neurogenic lower urinary tract dysfunction is common among people with multiple sclerosis (MS).
NCT06341673
·
Khobar, Eastern Providence
Completed
Interventional Clinical Trial for CCSVI in Multiple Sclerosis Patients
To investigate the safety and tolerability of balloon venoplasty compared to sham in Multiple Sclerosis patients with Chronic Cerebrospinal Venous Insufficiency (CCSVI) as…
NCT01864941
·
Vancouver, British Columbia and 3 others
Completed
A Pilot Nutrition Program for Spinal Cord Injury and MS
The purpose of this study is to determine the feasibility of a 12-week pilot community-based nutrition program for individuals with spinal cord injury and multiple sclerosis, and…
NCT03977922
·
Saint Catharines, Ontario
Terminated
Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)
The primary objective of Part 1 of this study is to evaluate the effects of BIIB033 versus placebo on disability improvement over 72 weeks.
NCT03222973
·
Cullman, Alabama and 158 others
Completed
Avonex (Interferon-beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-remitting MS
The primary objective of this study is to determine whether combination treatment (adding methylprednisolone to Avonex) reduces progression of disability over 4 years compared to…
NCT00168766
·
Brussels and 8 others
Completed
Pilot Clinical Trial of ACTHar Gel 14 Days Subcutaneous (SQ)Versus ACTHar Gel Five Days SQ for the Treatment of MS Exacerbations
This pilot study is designed as a prospective cohort study to determine whether standard subcutaneous (SQ) Highly-Purified (HP) Acthar Gel 14 days is superior to SQ HP Acthar Gel…
NCT01888354
·
Oceanside, California and 1 other
Recruiting
Assessment of Synaptic Density in MS
The investigators propose to use the novel SV2a-PET ligand, \[F-18\]SDM-8 to assess synaptic density in progressive multiple sclerosis (PMS) (including primary progressive…
NCT04634994
·
Boston, Massachusetts
Unknown
RItuximab Long-Term DOSE Trial in Multiple Sclerosis - RIDOSE-MS
A randomized trial of long-term dosage of rituximab in multiple sclerosis
NCT03979456
·
Danderyd, Stockholm County and 16 others
Completed
Study Evaluating Kesimpta® Treatment Effects in Patients With Relapsing Multiple Sclerosis Transitioning From Other Therapies
KAIROS was a prospective, multicenter, non-interventional study (NIS) in Germany.
NCT05566756
·
Mannheim, Baden-Wurttemberg and 39 others
Completed
A Study to Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis
This is a Phase II/III, randomized, double-blind, parallel group, placebo controlled, multicenter study to evaluate the safety and efficacy of rituximab in adults with PPMS.
NCT00087529
Completed
Waking Hypnosis in the Treatment of MS-related Fatigue
The proposed study is a single-center, single-blind three-group randomized (1:1:1) controlled trial (RCT) comparing two hypnosis interventions to waitlist control efficacy for…
NCT04429789
·
Seattle, Washington
Unknown
Stratifying Risk for Intracerebral Haemorrhage
This study aims to investigates the role of gestational age on the prevalence of coagulation factors and components of the complement system in preterm- (≤32+0 weeks) and term…
NCT04140812
·
Erlangen, Bavaria
Recruiting
3D OPTIMIZED WMN MPRAGE Increased Detection of Focal Spinal Cord Lesion in Multiple Sclerosis (WHINUME)
The aim of this study is to compare the 3D OPTIMIZED MPRAGE WMN sequence to "conventional sequences" used in spinal cord analysis.
NCT05227092
·
Bordeaux
Completed
Evaluation of the Positron Emission Tomography (PET) Tracer ZK 6032924 in Patients With Multiple Sclerosis Compared to Healthy Volunteers
PET (positron emission tomography) imaging with BAY85-8101 for investigation in patients with Multiple Sclerosis compared to healthy volunteers
NCT01031199
·
Heidelberg, Victoria and 1 other
Terminated
Targeted Lower Extremity Joint Training
The presence of foot drop limits normal gait. Our prior data has suggested that approximately 30% of MS patients have foot drop.
NCT00765544
·
Providence, Rhode Island
Completed
Advanced MRI Measures of Repair in Alemtuzumab Treated Patients
There are two parts to this investigator sponsored trial (IST): 1. To perform advanced serial MRI studies on patients initiating alemtuzumab therapy.
NCT01307332
·
Vancouver, British Columbia
Not yet recruiting
My MS Toolkit: An Internet-Based Depression Self-Management Program for Adults Living With Multiple Sclerosis
We are conducting this study to test if the new Toolkit depression module is accessible and helpful for people with multiple sclerosis (MS) in decreasing depression severity.
NCT07636434
·
Seattle, Washington
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