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1–20 of 3,499
Active not recruiting
Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer
This is a Phase 2, single-center study to explore the efficacy, safety, and tolerability of up to two 25-mg doses of psilocybin administered at an interval of 9 to 10 weeks in…
NCT05947383
·
Rockville, Maryland
Completed
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-073)
A clinical study to determine the efficacy and safety of MK0869 in the treatment of depression.
NCT00042029
Completed
Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study
This is a validation study that will replicate a completed study designed to assess biomarkers of treatment response to standard antidepressant treatment.
NCT04162522
·
Calgary, Alberta and 5 others
Withdrawn
A Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode
The purpose of this study is to evaluate flexible doses (5-30 mg) of aripiprazole in patients with bipolar depression.
NCT00338273
·
Durham, North Carolina and 7 others
Completed
Pre-mapping Networks for Brain Stimulation 2
The investigators compare the primary and secondary outcome measures using accelerated intermittent theta burst stimulation (aiTBS, 20 sessions active and 20 sessions sham in a…
NCT05260086
·
Göttingen
Completed
Safety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive Disorder
An outpatient study to evaluate the safety and efficacy of cariprazine as adjunct to antidepressant therapy (ADT) in participants with major depressive disorder (MDD) who have an…
NCT01469377
·
Garden Grove, California and 71 others
Completed
Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators
The investigators propose a one-year, repeated measures, within-subject design to examine the impact of improved caregiver depression on child asthma outcomes.
NCT02809677
·
Dallas, Texas
Completed
Effectiveness of a Structured Physical Rehabilitation Program for Chinese Patients With Depressive Disorders
Evidence shows that depression was found to be associated with physical inactivity and on the other hand, high prevalence of depression was also found in patients with chronic…
NCT01536756
·
Hong Kong and 1 other
Active not recruiting
Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)
This study will recruit 30 subjects diagnosed with Major Depressive Disorder (MDD).
NCT04846829
·
Los Angeles, California
Withdrawn
Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and Depression
The investigators will acquire simultaneous EEG and fMRI data from Veterans with depression and schizophrenia and mentally healthy Veterans to assess early sensory responses…
NCT03758495
·
San Francisco, California
Completed
Auricular Acupuncture vs. Progressive Muscle Relaxation in Patients With Anxiety Disorders or Major Depressive Disorder.
The purpose of this study is to determine whether auricular acupuncture (AA) according to the NADA protocol and progressive muscle relaxation (PMR) differ in their effectiveness…
NCT02340351
Unknown
The Efficacy of Acupressure Therapy on Patient With Depression
A new nursing intervention with non-invasive acupressure protocol for activation of parasympathetic nervous system to reduce stress related depression symptoms.
NCT05423405
Completed
Mechanisms of Emotion Regulation Underlying Successful CBT in Depression
This research aims to elucidate mechanisms through which change occurs during cognitive behavior therapy (CBT) for depression.
NCT04328103
·
New York, New York
Completed
Therapist-Guided Smartphone-Delivered CBT for MDD
We are testing a smartphone app that provides therapy for depression. Participants will also receive short weekly virtual appointments with a therapist.
NCT05386329
·
Boston, Massachusetts
Completed
Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)
To assess the long-term safety and tolerability of oral OPC-34712 (brexpiprazole), given in addition to an FDA approved antidepressant (ADT) for the treatment of adults with Major…
NCT01360866
·
Birmingham, Alabama and 141 others
Unknown
A Transdiagnostic Sleep and Circadian Treatment for Major Depressive Disorder
This study will examine the use of a transdiagnostic Sleep and Circadian Treatment (TranS-C) in treating Major Depressive Disorder (MDD) in Chinese adults.
NCT03786731
·
Hong Kong
Completed
Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing Strategies
The purpose of the study aims to determine whether different concentrations of nitrous oxide (N2O) have different antidepressant effects for adults with treatment-resistant major…
NCT03283670
·
St Louis, Missouri
Enrolling by invitation
Precision Care for Major Depressive Disorder
This study aims to assess whether phenotyping-guided intervention selection is superior to intervention selection without phenotyping guidance (i.e., routine clinician and patient…
NCT06580041
·
San Francisco, California
Completed
Major Depressive Disorder With Mixed Features - Extension
Lurasidone HCl is a compound that is a candidate for the treatment of major depressive with mixed features.This clinical study is designed to test how well Lurasidone works to…
NCT01423253
·
Birmingham, Alabama and 16 others
Completed
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
The primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness…
NCT00518986
·
Jasper, Alabama and 61 others
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