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1–20 of 13,589
Completed
A Study to Assess Safety of Nivolumab in Routine Oncology Practice in China
The purpose of this study is to assess the safety of nivolumab in routine cancer practice in China.
NCT04825873
·
Beijing, Beijing Municipality and 1 other
Completed
hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse
This is a Phase I, open label study to evaluate the safety, tolerability, and immunogenicity of INO-1400 or INO-1401 alone or in combination with INO-9012, delivered by…
NCT02960594
·
Detroit, Michigan and 5 others
Completed
Early Hippocampal Avoidance Prophylactic Cranial Irradiation in Patients With LD SCLC
The main objective of this trial is to assess NCF after early HA-PCI concomitant to the second cycle of CHT and to tRT for patients with LD SCLC.
NCT02058056
·
Basel and 7 others
Completed
MEK Inhibitor and Thoracic Radiotherapy Trial
Two thirds of non small cell lung cancer patients present with locally advanced tumours (stage III) or metastatic disease (stage IV) and radiotherapy plays a major role in their…
NCT01146756
·
Manchester, Greater Manchester
Completed
Trial of PI-88 With Docetaxel in Advanced Non-Small-Cell Lung Cancer (NSCLC)
PI-88 is a new experimental drug that inhibits tumour growth by reducing the formation of new blood vessels into tumours.
NCT00097851
·
Camperdown, New South Wales and 12 others
Completed
Disease Characteristics, Treatment Patterns and Clinical Outcomes in Patients With Newly Diagnosed Unresectable Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) in China
The purpose of this observational study is to describe patient and disease characteristics as well as treatment patterns in Chinese patients with unresectable stage IIIB or IV…
NCT02458651
·
Beijing and 10 others
Active not recruiting
A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab
This study aims to establish a safe and well tolerated dose of \[177Lu\]Lu-DOTA-TATE in combination with carboplatin, etoposide and atezolizumab in this setting and to assess…
NCT05142696
·
Orlando, Florida and 26 others
Completed
Early Detection of Lung Cancer With Low-dose Multislice Computed Tomography
Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival.
NCT02754388
Completed
Pembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002, KEYVIBE-002)
The main purpose of this study is to compare pembrolizumab/vibostolimab coformulation (MK-7684A) plus docetaxel or pembrolizumab/vibostolimab coformulation to normal saline…
NCT04725188
·
Los Angeles, California and 94 others
Not yet recruiting
Impact of Psychological Stress on Treatment Response and Prognosis in Lung Cancer Patients
This study explores how psychological stress may influence the treatment response and long-term outcomes in patients with lung cancer.
NCT06964503
Completed
Evaluate the Impact of Afatinib on Quality of Life and Symptom Burden of Greek Subjects With Advanced NSCLC in Routine Patient Care Settings
This non-interventional study will include a representative sample of patients with locally advanced or metastatic NSCLC harboring Epidermal Growth Factor Receptor…
NCT02440854
·
Alexandroupoli and 6 others
Completed
Support Needs and Preferences of Family Caregivers of Lung Cancer Patients
This study is being done to learn what the needs are in relation to the family members. Some family members seek counseling; others do not.
NCT00967083
·
Jamaica, New York and 1 other
Completed
[18F]HX4 PET/CT Imaging for Detection of Hypoxia
The aim of this study is to investigate the radiotracer \[18F\]HX4 for non-invasive detection of hypoxia in patients with head and neck, or lung cancer.
NCT02976883
·
Nottingham, Nottinghamshire
Active not recruiting
Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)
The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor…
NCT06305754
·
Oakland, California and 155 others
Completed
Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer
This phase II trial studies how well talazoparib works in treating patients with homologous recombination repair deficiency (HRRD) positive stage IV squamous cell lung cancer that…
NCT03377556
·
Birmingham, Alabama and 1156 others
Active not recruiting
A Study to Evaluate First-line Ipilimumab + Nivolumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
The purpose of this study is to collect and evaluate real-world data to describe the outcomes, patient characteristics, safety profile and treatment patterns of first-line…
NCT06487156
·
Naples
Recruiting
Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT
Tyrosine Kinase Inhibitors (TKIs) especially higher generation TKI have higher CNS penetration rates and have shown favorable response rates in brain metastases.
NCT05236946
·
Mumbai, Maharashtra
Terminated
Ridaforolimus With Cetuximab: Adv Non-Small Cell Lung, Colorectal, Head & Neck Cancer
The main purpose of this study is to evaluate the best dose, safety and side effects of ridaforolimus when given with cetuximab for patients with head and neck, lung and colon…
NCT01212627
·
Pawtucket, Rhode Island and 1 other
Recruiting
Sample Collection for Ongoing Research and Product Evaluation Study
The SCORE study is a prospective, multi-site clinical trial designed to collect blood and tissue samples, along with relevant clinical data, from participants diagnosed with…
NCT07318051
·
Austin, Texas
Completed
Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
NCT00057837
·
Lewes, Delaware and 78 others
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