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1–20 of 3,585
Terminated
Confocal Laser Endomicroscopy (CLE) During Medically Induced Neurosurgery in Craniobasal and Glioma Tumours
Purpose of the study is to answer the question whether confocal laser endomicroscopy (CLE, also named 'optical biopsy') might improve the results of medically necessary…
NCT02491827
·
Cologne-Merheim, North Rhine Westfalia
Unknown
Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases
Cerebral metastases are common intracranial tumor, its incidence increased year by year, in recent years, although the whole brain radiation therapy, surgical resection…
NCT05459441
·
Shanghai, Shanghai Municipality
Active not recruiting
Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma
This study will investigate different doses of \[177Lu\]Lu-NeoB in combination with RT and TMZ in participants with newly diagnosed glioblastoma, with methylated or unmethylated…
NCT05739942
·
Los Angeles, California and 15 others
Recruiting
A Registry-Based Cohort Study on the Clinical Outcomes of Spinal Cord Glioma Resection Via the Dorsolateral Sulcus Approach
Spinal cord gliomas are the most common type of primary intramedullary malignant tumors, with a low incidence and a peak onset age of approximately 35 years.
NCT07066475
·
Beijing, Beijing Municipality
Terminated
Spatial Analysis and Validation of Glioblastoma on 7 T MRI
Currently, patients with a glioblastoma multiforme (GBM) are treated with a combination of different therapeutic modalities including resection, concurrent chemo- and radiotherapy…
NCT02062372
·
Maastricht, Limburg
Terminated
Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205
Participants that were assigned to the oral etoposide treatment arm in protocol OSI-774-205 and either progressed while on study or discontinued due to unacceptable toxicity…
NCT01247922
·
Birmingham, Alabama and 20 others
Recruiting
Natural History Study of Patients With Neurofibromatosis Type 2
Objective With this prospective natural experiment trial on neurofibromatosis type 2 (NF2) study, we hope to understand the factors leading to tumor progression and neurological…
NCT00598351
·
Bethesda, Maryland
Terminated
Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM
Objectives: 1.
NCT00508456
·
Houston, Texas
Recruiting
CARv3-TEAM-E T Cells in Glioblastoma
The goal of this research study is to determine the best dose of CARv3-TEAM-E T Cells for treating participants with glioblastoma.
NCT05660369
·
Boston, Massachusetts
Completed
Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma
This is a pilot study to assess the ability of \[F-18\]fluciclovine to differentiate pseudoprogression from progression in participants after therapy, at imaging time points…
NCT04114370
·
Pittsburgh, Pennsylvania
Completed
Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer
RATIONALE: Everolimus may stop the growth of tumor cells by stopping blood flow to the tumor.
NCT00085566
·
New York, New York and 1 other
Completed
Evaluating Therapeutic Response to Novo-TTF
This study is to assess the utility of high resolution 3D echo planar magnetic resonance spectroscopy (3D EPSI) in monitoring Novo-TTF response in glioblastoma multiforme (GBM)…
NCT02441322
·
Philadelphia, Pennsylvania
Completed
Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma
This phase I/II trial studies the side effects and best dose of vorinostat and to see how well it works when given together with radiation therapy followed by maintenance therapy…
NCT01189266
·
Birmingham, Alabama and 179 others
Terminated
[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers
This phase I trial studies how well \[18F\]DASA-23 and positron emission tomography (PET) scan work in evaluating pyruvate kinase M2 (PKM2) expression in patients with…
NCT03539731
·
Palo Alto, California
Completed
5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor
In support of the US marketing application for 5-ALA, this single arm trial is being conducted to establish the efficacy and safety of Gliolan® (5-ALA) in patients with newly…
NCT02632370
·
Washington D.C., District of Columbia and 16 others
Recruiting
Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade Gliomas
The LoG-Glio-Registry is based on a network of german hospitals gathering radiological, clinical, epidemiological and molecular data on all patients diagnosed with a low grade…
NCT02686229
·
Ulm
Withdrawn
Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors
RATIONALE: New imaging procedures, such as functional magnetic resonance imaging and 1H-nuclear magnetic resonance spectroscopic imaging, may improve the ability to detect the…
NCT00005083
Recruiting
CEST in Low-grade Glioma Study
Low grade gliomas (LGGs) are malignant, infiltrative and incurable brain tumours that typically present in the younger population.
NCT05996653
·
Toronto, Ontario and 1 other
Completed
Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma
This randomized phase III trial studies temozolomide (TMZ) and radiation therapy (RT) to compare how well they work with or without bevacizumab in treating patients with newly…
NCT00884741
·
Mobile, Alabama and 329 others
Unknown
Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study
Knowledge of the spatial extent of gliomas is an essential prerequisite for the treatment planning.
NCT02941302
·
Yinchuan, Ningxia
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