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NCT07451990
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy. Proper closure of the abdominal wall is important to reduce complications such as wound dehiscence and surgical site infection. Adult patients undergoing elective midline laparotomy were randomly assigned to rectus sheath closure using either Prolene or Vicryl sutures. All patients received the same standardized surgical technique and postoperative care. Participants were followed for 30 days after surgery to assess wound healing, wound dehiscence, surgical site infection, and length of hospital stay. The study aimed to determine which suture material is associated with fewer postoperative wound complications.
NCT07241507
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications. Specifically, the study aims to find out if using interrupted sutures results in fewer cases of wound dehiscence (wound reopening) compared to continuous sutures. The main question the study seeks to answer is: Does interrupted suturing reduce the frequency of wound dehiscence compared to continuous suturing in patients undergoing exploratory laparotomy? Researchers will also observe and compare wound infection rates between the two suturing methods. About 80 adult patients (18-60 years old) undergoing exploratory laparotomy at the Department of General Surgery, DHQ Teaching Hospital, Dera Ghazi Khan, will take part in this study. Participants will be randomly assigned to one of two groups: Group A: Continuous abdominal closure using No. 1 Vicryl suture Group B: Interrupted abdominal closure using No. 1 Vicryl suture All participants will have their baseline characteristics recorded, including age, gender, obesity, diabetes, and smoking status. The surgical technique and postoperative care will follow the hospital's standard protocols. After surgery, patients will be followed for four weeks with weekly clinical assessments to check for wound infection or wound dehiscence. The hypothesis is that patients whose abdominal wounds are closed with interrupted sutures will have a lower frequency of wound dehiscence compared to those with continuous sutures. The findings will help guide surgeons on which abdominal closure method provides better wound healing and fewer postoperative complications.
NCT07142395
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or waiting a few days before closing the skin (called delayed primary closure). Wound infection is a common problem after emergency abdominal surgery (also called laparotomy). Some surgeons close the skin right away, while others wait a few days to reduce the risk of infection. This study will help find out which method is better. The main questions the study aims to answer are: 1. . Does delayed primary closure lower the rate of wound infection compared to primary closure? 2. . Does the wound open up (wound dehiscence) less often with delayed closure? 3. . Does delayed closure affect the length of hospital stay? In this clinical trial: * Adult patients needing emergency abdominal surgery will be included. * Half the patients will have their wounds closed immediately (primary closure), and half will have delayed closure after 3-5 days of daily dressing. * All surgeries will be done by experienced surgeons using the same technique. * Patients will be followed for 4 weeks after surgery to monitor wound infection, wound opening, and length of hospital stay. The results will help doctors choose the safest and most effective way to close surgical wounds after emergency abdominal surgery.