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Clinical Trials in Washington | 9,462 Studies Near You | Clareo Health

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Clinical Trials in Washington

Discover 9,462 clinical trials near Washington. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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Showing 8221-8240 of 9,462 trials

COMPLETEDPhase 336 miles

Study of Aripiprazole in the Treatment of Patients With Acute Symptoms of Bipolar Disorder

NCT00046384

The purpose of this study is to learn if aripiprazole is effective in the treatment of patients with acute symptoms of Bipolar Disorder.

Bipolar I Disorder

Otsuka Pharmaceutical Development & Commercialization, Inc.Started Jun 2002

Scottsdale, Arizona, United States • Little Rock, Arkansas, United States • Chula Vista, California, United States +11 more locations

COMPLETEDPhase 336 miles

A Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode

NCT00094432

The purpose of this study is to evaluate several doses of aripiprazole in patients with bipolar depression.

Bipolar I Disorder

Otsuka Pharmaceutical Development & Commercialization, Inc.650 participantsStarted Jun 2004

Mesa, Arizona, United States • La Mesa, California, United States • La Palma, California, United States +37 more locations

Find Trials by Condition in Washington

Breast Cancerin Washington Lung Cancerin Washington Prostate Cancerin Washington Colorectal Cancerin Washington Melanomain Washington Leukemiain Washington Lymphomain Washington Pancreatic Cancerin Washington Ovarian Cancerin Washington Brain Cancerin Washington

Data from ClinicalTrials.govTerms

COMPLETEDPhase 336 miles

A Long-Term Study of Aripiprazole in Patients With Major Depressive Disorder

NCT00095745

This trial is a 52-week safety study to evaluate the safety of adjunctive aripiprazole in outpatients with major depressive disorder who have experienced an incomplete response to an ongoing antidepressant trial.

Major Depressive Disorder

Otsuka Pharmaceutical Development & Commercialization, Inc.1,002 participantsStarted Sep 2004

Mesa, Arizona, United States • Peoria, Arizona, United States • Beverly Hills, California, United States +55 more locations

COMPLETEDPhase 239 miles

Phase 2b Study of Cetuximab With Platinum-Based Chemo as First Line Treatment of Recurrent or Advanced NSCLC

NCT00828841

This study is testing the investigational drug, cetuximab, in combination with different chemotherapy drugs for lung cancer. The aim of the study is to determine which of the drug combinations looks most promising and should be tested further. The study will also look at what side effects may occur.

Non-Small Cell Lung Cancer

Accelerated Community Oncology Research Network601 participantsStarted Dec 2008

Anniston, Alabama, United States • Jonesboro, Arkansas, United States • Anaheim, California, United States +81 more locations

COMPLETED42 miles

Natural History of Human Papillomavirus (HPV) Infections in Mid-Adult Women (WHIM)

NCT01295242

The purpose of this study is to determine rates of oral and genital human papillomavirus (HPV) infections, and look at risk factors for HPV infection in healthy mid-adult women.

Papillomavirus Infections

University of Washington409 participantsStarted Feb 2011

Seattle, Washington, United States

COMPLETEDPhase 342 miles

A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches

NCT00156910

This is a 60 week study including a double-blind phase followed by an open-label extension phase.

Migraine Disorders

Allergan679 participantsStarted Feb 2006

Seattle, Washington, United States • Markham, Ontario, Canada

COMPLETEDPhase 242 miles

A Chemoprevention Study of an Investigational Drug in Men With High Grade Prostate Intraepithelial Neoplasia (PIN)

NCT00028353

If you are a male 30 years of age or older and have a positive diagnosis of high grade (II or III) prostate Intraepithelial Neoplasia (PIN) or have had an abnormal/suspicious prostate biopsy, you may be eligible for this study. This is a study of an investigational medication that may reduce high grade PIN and prevent the occurrence of prostate cancer. This study is currently enrolling up to 500 men at approximately 60 locations in the United States.

Prostatic Intraepithelial Neoplasia

GTx500 participantsStarted Apr 2001

Huntsville, Alabama, United States • Little Rock, Arkansas, United States • Aventura, Florida, United States +22 more locations

COMPLETEDPhase 2/342 miles

PROS-1-Male Hormonal Contraceptive Regimens on Prostate Tissue

NCT00490555

The investigators propose to examine the in vivo responses to hormonal manipulation at the molecular level directly in the tissue of interest (prostate). As in the investigators' previous, pilot study, the investigators will use the novel approach of procuring tissue specimens from normal, healthy men who might be chose to use a male hormonal contraceptive regimen were it available. The investigators will employ state of the art techniques such as laser capture microdissection (LCM) and cDNA microarrays to determine the tissue-specific consequences of male hormonal contraceptive regimens on the prostate. The results will help guide the design, safety monitoring, and selection of male hormonal contraceptive agents and provide valuable insights into prostate human prostate biology. The investigators will test the hypothesis that exogenous T administration that results in increased circulating T and dihydrotestosterone (DHT) levels will increase intraprostatic concentrations of T and its metabolite DHT. The investigators will test the hypothesis that the addition of a potent 5α-reductase inhibitor, dutasteride, or the progestin, Depomedoxyprogesterone (IM DMPA), to T administration in young and middle aged men will decrease intraprostatic DHT and increase intraprostatic T concentrations compared to T alone. The investigators will test the hypothesis that the addition of a 5α-reductase inhibitor dutasteride or the progestin IM DMPA to exogenous T, by reducing intraprostatic DHT, will decrease prostate epithelial proliferation, assessed by Ki-67 labeling index (Ki-67LI), and increase apoptosis, assessed by caspase-3 expression, and decrease androgen-regulated protein expression such as prostate specific antigen (PSA). The investigators will test the hypothesis that the addition of a 5α-reductase inhibitor or the progestin IM DMPA to exogenous T, by modifying the intraprostatic hormonal milieu, will alter prostate epithelial gene expression. Specifically, the investigators expect that the addition of the 5α-reductase inhibitor dutasteride or the progestin IM DMPA to exogenous T, will result in decreased expression of androgen-regulated genes such as PSA.

University of Washington32 participantsStarted Jan 2009

Seattle, Washington, United States

COMPLETEDPhase 242 miles

Radiation Therapy Plus Paclitaxel in Treating Patients With Nonmetastatic, Unresectable Pancreatic Cancer

NCT00003591

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of radiation therapy plus paclitaxel in treating patients who have nonmetastatic, unresectable pancreatic cancer.

Pancreatic Cancer

Radiation Therapy Oncology Group122 participantsStarted Nov 1998

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +231 more locations

COMPLETED42 miles

Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy

NCT00021866

The purpose of this study is to determine if antiepileptic drugs (AEDs) differ in their neurodevelopmental effects. Specifically, do the children of the women with epilepsy differ in their behavioral and cognitive development depending on which AED their mother takes during pregnancy?

EpilepsySeizureCognition Disorders

Emory University331 participantsStarted Sep 2000

Birmingham, Alabama, United States • Tucson, Arizona, United States • Los Angeles, California, United States +18 more locations

UNKNOWNPhase 242 miles

Monoclonal Antibody Therapy in Treating Patients With Residual Disease From Stage III or Stage IV Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer Following Surgery and Chemotherapy

NCT00003634

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. It is not yet known whether giving monoclonal antibody therapy is more effective than a placebo in treating patients with ovarian epithelial, fallopian tube, or peritoneal cancer who have responded to surgery and chemotherapy. PURPOSE: Randomized phase II trial to study the effectiveness of monoclonal antibody therapy in treating patients with residual disease from stage III or stage IV ovarian epithelial, fallopian tube, or peritoneal cancer following surgery and chemotherapy.

Fallopian Tube CancerOvarian CancerPrimary Peritoneal Cavity Cancer

AltaRex400 participantsStarted Apr 1998

Berkeley, California, United States • Los Angeles, California, United States • Los Angeles, California, United States +43 more locations

UNKNOWNPhase 342 miles

T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum

NCT00002811

RATIONALE: Patients with xeroderma pigmentosum are more likely to develop skin lesions in sun-affected areas. These skin lesions, such as actinic keratoses, can develop into skin cancer. T4N5 liposome lotion may reduce actinic keratoses or other sun-induced skin damage in patients with xeroderma pigmentosum. PURPOSE: Randomized double-blinded phase III trial to compare treatment using T4N5 liposome lotion with treatment using placebo in reducing actinic keratoses and other sun-induced skin damage in patients with xeroderma pigmentosum.

Precancerous Condition

Applied Genetics30 participantsStarted Jul 1996

Miami Beach, Florida, United States • Ann Arbor, Michigan, United States • Minneapolis, Minnesota, United States +6 more locations

UNKNOWNPhase 246 miles

Microwave Thermotherapy in Treating Women With Stage I or Stage II Breast Cancer

NCT00036998

RATIONALE: Microwave thermotherapy kills tumor cells by heating them to several degrees above body temperature. PURPOSE: Randomized phase II trial to compare the effectiveness of microwave thermotherapy before surgery to that of surgery alone in treating women who have stage I or stage II breast cancer.

ImunonStarted Aug 2001

Los Angeles, California, United States • Orange, California, United States • Coral Springs, Florida, United States +5 more locations

COMPLETEDPhase 246 miles

Investigation of Efficacy, Safety and Tolerability of Once and Twice Daily Doses of AZD1981 in Asthmatic Patients

NCT01197794

The study will assess the efficacy, safety and tolerability of AZD1981 compared to non-active compound in asthmatic patients.

Asthma Patients

AstraZeneca1,144 participantsStarted Oct 2010

Fullerton, California, United States • Los Angeles, California, United States • Mission Viejo, California, United States +102 more locations

COMPLETEDPhase 3112 miles

Spiriva® Assessment of FEV1 (SAFE)

NCT00277264

The objective of this trial is to evaluate whether the effect of one year (48 weeks) treatment with inhaled tiotropium bromide (Spiriva® - 18 µg once daily) on the change in trough FEV1, compared to placebo in patients with COPD, is affected by smoking status.

Pulmonary Disease, Chronic Obstructive

Boehringer Ingelheim914 participantsStarted Jan 2002

Calgary, Alberta, Canada • Calgary, Alberta, Canada • Calgary, Alberta, Canada +93 more locations

COMPLETEDPhase 2148 miles

Trial to Evaluate the Therapeutic Benefit of Fulvestrant in Combination With ZACTIMA in Postmenopausal Women With Bone Predominant, Hormone Receptor Positive Metastatic Breast Cancer

NCT00811369

The purpose of this study is to evaluate whether the combination of fulvestrant and ZACTIMA, versus fulvestrant plus placebo, results in a significant decrease in the bone marker, urinary N-Telopeptide (NTx) in postmenopausal women with bone only, or bone predominant, hormone receptor-positive metastatic breast cancer. A significant decrease will be defined as a \> 30% reduction in urinary NTx level from baseline.

Metastatic Breast Cancer

Ontario Clinical Oncology Group (OCOG)126 participantsStarted Aug 2009

Edmonton, Alberta, Canada • Vancouver, British Columbia, Canada • Halifax, Nova Scotia, Canada +10 more locations

COMPLETEDPhase 2148 miles

Efficacy of TPI ASM8 During a 14-Day Allergen Challenge

NCT01158898

This is a randomized, double-blind, placebo-controlled, 3-way crossover trial to evaluate the efficacy and safety of two different doses of inhaled TPI ASM8 administered daily for 14 days for the treatment of allergic asthma and allergen-induced asthma.

Syntara16 participantsStarted Nov 2010

Calgary, Alberta, Canada • Vancouver, British Columbia, Canada • Hamilton, Ontario, Canada +1 more locations

COMPLETEDPhase 3148 miles

Cytarabine With or Without VNP40101M in Treating Patients With Relapsed Acute Myeloid Leukemia

NCT00112554

RATIONALE: Drugs used in chemotherapy, such as cytarabine and VNP40101M, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. PURPOSE: This randomized phase III trial is studying cytarabine and VNP40101M to see how well they work compared to cytarabine alone in treating patients with relapsed acute myeloid leukemia.

Vion Pharmaceuticals420 participantsStarted Mar 2005

Los Angeles, California, United States • Los Angeles, California, United States • Orange, California, United States +59 more locations

COMPLETED418 miles

Impulse Control Disorders in Parkinson's Patients Treated With Pramipexole and Other Agents (DOMINION Study)

NCT00617019

The purpose is to explore the frequency of impulse control disorders in Parkinson's patients treated with different Parkinson's medications.

Parkinson Disease

Boehringer Ingelheim3,234 participantsStarted Sep 2006

Gilbert, Arizona, United States • Scottsdale, Arizona, United States • Sun City, Arizona, United States +46 more locations

TERMINATEDPhase 2689 miles

S9624 Ifosfamide in Treating Patients With Meningeal Tumors

NCT00003292

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of ifosfamide in treating patients with meningeal tumors that have recurred or that cannot be removed surgically.

ChondrosarcomaAdult FibrosarcomaAdult Leiomyosarcoma+3 more

SWOG Cancer Research Network7 participantsStarted Jul 1998

Scottsdale, Arizona, United States • Duarte, California, United States • Palo Alto, California, United States +67 more locations

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