Clinical Trials in Texas

Showing 6241-6260 of 15,101 trials

Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation

NCT04035200

The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with alcohol use disorder (AUD) who experience insomnia associated with alcohol cessation, compared to placebo.

Insomnia

Imbrium Therapeutics114 participantsStarted Sep 2019

Glendale, California, United States • Riverside, California, United States • San Diego, California, United States +14 more locations

TERMINATEDPhase 155 miles

Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies

NCT04865159

A Phase I, open-label clinical pharmacology study designed to evaluate the effect of tipifarnib on cardiac repolarization (corrected QT interval \[QTc\] duration) following a single dose of 900 mg and after repeated twice daily administration of 600 mg in subjects with advanced solid malignancies. Subjects will receive a 900 mg single dose at cycle 1 day 1 follow by 600 mg twice a day orally with a meal (Days 2-7 and 15-21) in 28-day cycles. Beginning on Day 2 of Cycle 1, subjects will self-administer 600 mg tipifarnib, orally with a meal, bid for 7 days in alternating weeks (Days 2-7 and 15-21) in 28-day cycles. The secondary objectives are to evaluate the safety and PK of tipifarnib. Series of PK will be collected on day -1 of Cycle 1, Cycle 1 day 1 and Cycle 1 day 7.

Advanced Solid Tumor

Kura Oncology, Inc.6 participantsStarted May 2021

Canton, Ohio, United States • Austin, Texas, United States • San Antonio, Texas, United States

Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation

Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies

Find Trials by Condition in Texas

Subchondroplasty® Knee RCT

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD

Study of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Patients With Metastatic Breast Cancer (MK-7962-012)

Addressing Dementia Via Agitation-Centered Evaluation

An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants

A Study Assessing the Safety and Effectiveness of IC2000 and SPY Fluorescence Imaging Systems (SPY-PHI) in the Visualization of Lymphatic Vessels and Identification of Lymph Nodes During Sentinel Lymph Node Biopsy in Subjects With Breast Cancer

Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-201 in Subjects Ages 16-35 With Peanut Allergy

Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients

Bioaerosol Sampling Device (BSD) Clinical Study

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

A Study of BTX-1188 in Subjects With Advanced Malignancies

Evaluating the Effects of Tasimelteon vs. Placebo on Jet Lag Type Insomnia

INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens

39946-I Laser and Bevacizumab Treatment for Retinopathy of Prematurity

Study of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel Chemotherapy

Human Epilepsy Project 2: Resistant Focal Seizures Study

Multi-Center Pilot Study of truSculpt Device