Clinical Trials in Tennessee

Showing 19261-19280 of 20,239 trials

Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan

NCT00473616

This is an open-label, multi-center, dose-escalation and safety expansion, Phase I study to evaluate the safety, tolerability, and pharmacokinectics and to investigate biomarker changes of AZD7762 administered as a single intravenous unit and in combination with irinotecan. The study is sponsored by AstraZeneca.

Advanced Solid TumorsCancerAdvanced Solid Malignancies

AstraZeneca60 participantsStarted May 2007

Boston, Massachusetts, United States • New York, New York, United States • Nashville, Tennessee, United States

COMPLETEDPhase 387 miles

Safety and Efficacy Study of PEG-uricase in the Treatment of Hyperuricemic Patients With Symptomatic Gout

NCT00325195

These are two replicate studies to evaluate the safety and efficacy of PEG (polyethylene glycol)-uricase in controlling the uric acid level in symptomatic gout patients with high uric acid levels who are unable to take standard gout therapies, or for whom those therapies have been unsuccessful in controlling their uric acid level.

Gout

Savient Pharmaceuticals225 participantsStarted May 2006

Birmingham, Alabama, United States • Tucson, Arizona, United States • Jonesboro, Arkansas, United States +53 more locations

Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan

Safety and Efficacy Study of PEG-uricase in the Treatment of Hyperuricemic Patients With Symptomatic Gout

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DPBRN Prevalence of Questionable Occlusal Caries Lesions

A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive Medications

Fesoterodine "add-on" Male Overactive Bladder Study

Study of Milnacipran Added to Pregabalin for Treatment of Fibromyalgia

Valganciclovir in Congenital CMV Infants

Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD

Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis

Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV

Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer

Study Tests The Safety And Effectiveness Of SU011248 In Patients With Non-Small Cell Lung Cancer Having Brain Metastases

Carbidopa/Levodopa/Entacapone Versus Immediate Release (IR) Carbidopa/Levodopa on Non-motor Symptoms in Patients With Idiopathic Parkinson's Disease and Demonstrating Non-motor Symptoms of Wearing Off

A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS

A Study to Evaluate the Effects of Different Methods of Birth Control on the Drug Actions of Zidovudine (an Anti-HIV Drug) in HIV-Positive Women and to Compare Zidovudine Metabolism in Men and Women

A Dose Escalation and Safety Study of I5NP in Patients Undergoing Major Cardiovascular Surgery

A Multicenter, Open Label, Single Dose Study to Evaluate the Effect of Renal Insufficiency on the Pharmacokinetics of SK 0403

Glutamine in Treating Side Effects in Children Who Are Undergoing Stem Cell Transplantation

A Study of Nevirapine Used Alone or in Combination With AZT in HIV-1-Infected Children

Evaluation of RTVue in Corneal Measurement