Clinical Trials in Tennessee

Showing 1501-1520 of 17,345 trials

QTX3544 in Patients With Advanced Solid Tumors With KRAS G12V Mutations

NCT06715124

Phase 1 study to determine the safety, tolerability, and anti-tumor activity of QTX3544 as a single agent or in combination with cetuximab.

Advanced Solid Tumors

Quanta Therapeutics237 participantsStarted Jan 2025

Denver, Colorado, United States • New Haven, Connecticut, United States • Sarasota, Florida, United States +7 more locations

Active Not RecruitingPhase 229 miles

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

NCT06727565

Master protocol: The main goal of this master clinical study is to evaluate the efficacy and safety of multiple novel combination therapies in participants with head and neck squamous cell carcinoma (HNSCC) in various substudies. Substudy-01 will evaluate the efficacy and safety of novel combination of treatment regimens, domvanalimab (DOM) and zimberelimab (ZIM) combined with chemotherapy vs ZIM combined with chemotherapy. The primary objective is to assess the efficacy of DOM and ZIM in combination with chemotherapy versus ZIM in combination with chemotherapy.

Head and Neck Squamous Cell Carcinoma

Gilead Sciences100 participantsStarted Feb 2025

St Louis, Missouri, United States • Nashville, Tennessee, United States • Houston, Texas, United States +20 more locations

QTX3544 in Patients With Advanced Solid Tumors With KRAS G12V Mutations

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

Find Trials by Condition in Tennessee

A Study of ASP3082 in Adults With Advanced Solid Tumors

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia

Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

Mobile Health for Adherence in Breast Cancer Patients

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST)

REALITY LHON Registry

A Dose Range-Finding Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD8630 in Adults With Uncontrolled Asthma at Risk of Exacerbations

Dose-Escalation Study of Cenobamate (YKP3089) in Pediatric Subjects With Partial-Onset Seizures

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Water Vapor Ablation for Localized Intermediate Risk Prostate Cancer

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta

Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants

TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury