Clinical Trials in Tennessee

Showing 11081-11100 of 20,239 trials

Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression

NCT03724968

This is an open-label, non-randomized two arm Phase 2 study of intravenous nivolumab plus intravenous ipilimumab or intravenous relatlimab in patients with metastatic melanoma stratified by MHC-II expression.

Metastatic MelanomaAdvanced MelanomaMetastatic Melanoma Stratified by MHC-II Expression

Elizabeth Davis2 participantsStarted Jan 2019

Nashville, Tennessee, United States

COMPLETEDPhase 329 miles

Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer

NCT00704730

The purpose of this research study is to evaluate the progression-free survival (PFS) with XL184 as compared with placebo (an inactive substance) in subjects with unresectable, locally advanced, or metastatic medullary thyroid cancer (MTC). Subjects will be randomized to receive XL184 or placebo in a 2:1 ratio. XL184 is an investigational drug that inhibits VEGFR2, MET and RET, kinases implicated in tumor formation, growth and migration. The Clinical Steering Committee for this study, comprised of study doctors who specialize in medullary thyroid cancer, has provided guidance regarding the design of the study. The committee includes: Douglas Ball, MD, Barry Nelkin, PhD, Martin Schlumberger, MD and Steven Sherman, MD.

Thyroid Cancer

Exelixis330 participantsStarted Jun 2008

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Little Rock, Arkansas, United States +110 more locations

Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression

Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer

Find Trials by Condition in Tennessee

Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer

A PK and Safety Evaluation of HORIZANT (Gabapentin Enacarbil) in Adolescents With Moderate-to-Severe Primary RLS

Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status

A Safety Extension Study With Benralizumab for Asthmatic Adults on Inhaled Corticosteroid Plus Long-acting β2 Agonist

Anti-VEGF vs. Prompt Vitrectomy for VH From PDR

A Multicenter Assessment of a Spontaneous Preterm Birth Risk Predictor

Open-Label Study to Evaluate Safety of A Single Dose of SYM-1219

A Phase II Study of M2951 in SLE

Study of Pediatric Migraine: The Pediatric Migraine Registry

A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia

A Clinical Study to Evaluate the Effect of the Connected Inhaler System (CIS) on Adherence to Maintenance Therapy in Poorly Controlled Asthmatic Subjects

UNITE Study: Understanding New Interventions With GBM ThErapy

Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder

Phase Ib Trial of LEE011 With Everolimus (RAD001) and Exemestane in the Treatment of Hormone Receptor Positive HER2 Negative Advanced Breast Cancer

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Treatment for Endogenous Cushing's Syndrome

Fuzzy Logic Automated Insulin Regulation

Effects of Cannabidiol on Psychiatric Symptoms, Cognition, and Cannabis Consumption in Cannabis Users With Recent-Onset Psychosis