Clinical Trials in Tennessee

Showing 7101-7120 of 20,239 trials

A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease

NCT06225973

In this prospective, phase 2b, multicenter, randomized, double-masked, vehicle-controlled, parallel-arm study, approximately 880 subjects with moderate to severe dry eye disease (DED) will be randomly assigned (1:1) to receive either TL-925 or vehicle as topical ophthalmic eye drops administered bilaterally BID. The study will comprise two phases: a two-week screening phase/run-in and a six-week double-masked treatment phase.

Dry Eye Disease

Telios Pharma, Inc.880 participantsStarted Feb 2024

Phoenix, Arizona, United States • Glendale, California, United States • La Mesa, California, United States +15 more locations

COMPLETEDNA20 miles

A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop

NCT04175340

The objective of this study is to evaluate the safety and effectiveness of lubricating and rewetting drop (Test) compared to OPTI-FREE® Replenish® Rewetting Drops (Control) when used by habitual contact lens wearers to bilaterally lubricate and rewet soft (hydrophilic) contact lenses including silicone hydrogel contact lenses and gas permeable (silicone acrylate and fluoro silicone acrylate) contact lenses.

Contact Lens Wear

Bausch & Lomb Incorporated369 participantsStarted Nov 2019

San Francisco, California, United States • Torrance, California, United States • Sarasota, Florida, United States +12 more locations

A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease

A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop

Find Trials by Condition in Tennessee

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease

Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Evaluating the Impact of the Bridge Clinic in Patients With Opioid Use Disorder

A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)

Study of RO7515629 in Participants With HLA-G Positive Solid Tumors

Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients

Impact of Microvascular Inflammation on Kidney Allograft Outcome

Study of ASN004 in Patients With Advanced Solid Tumors

Ibrexafungerp for the Treatment of Complicated Vulvovaginal Candidiasis

Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization

Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)

Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD)

Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders

Phase II Short-term Adjuvant Therapy and Biomarker Studies With Targeted Agents in Women With Estrogen Receptor Negative Breast Cancer

Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders

TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence

Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma