Clinical Trials in Tennessee

Showing 6401-6420 of 20,239 trials

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

NCT04366440

The overall objective of this study is to identify the best strategy to eliminate unnecessary antibiotic use after surgery in pediatric surgical procedures considered low-risk for an SSI. Based on literature and our preliminary data suggesting surgeons will not fully accept standardized order sets based on current guidelines, the investigators hypothesize that order set modification combined with ASP facilitation will outperform standard order set modification alone in de-implementing unnecessary postoperative antibiotic use.

Surgical Site Infection

Washington University School of Medicine39,363 participantsStarted Nov 2020

St. Petersburg, Florida, United States • Boston, Massachusetts, United States • Ann Arbor, Michigan, United States +7 more locations

COMPLETEDPhase 229 miles

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

NCT06097663

This Phase 2a clinical trial will evaluate the effectiveness, safety, and tolerability of increasing dose strengths of an oral daily medication, DFV890, administered for 12 weeks, or a single s.c. dose of MAS825, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 28 people with known coronary heart disease and TET2 or DNMT3A CHIP (VAF ≥2%).

Coronary Heart DiseaseClonal Hematopoiesis of Indeterminate Potential (CHIP)

Novartis Pharmaceuticals31 participantsStarted Feb 2024

St Louis, Missouri, United States • Nashville, Tennessee, United States • Montreal, Quebec, Canada +3 more locations

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

Find Trials by Condition in Tennessee

Prospective Evaluation of Efficacy and Safety of an Intense Pulsed Light Device to Treat Dry Eye Disease"

A Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations

realMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCL

Phase 1b, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Chronic Inducible Urticaria

GKT137831 in IPF Patients with Idiopathic Pulmonary Fibrosis

A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL

Study Evaluating the Efficacy and Safety of OCS-01 Eye Drops in Subjects Following Cataract Surgery

Efficacy and Safety of MK-1942 as an Adjunct Therapy in Participants With Mild to Moderate Alzheimer's Disease Dementia (MK-1942-008)

An Open-Label Study of Oral NNZ-2591 in Prader-Willi Syndrome (PWS-001)

A Long Term Extension Study to Assess the Safety of TB006 in Participants With Alzheimer's Disease

Study of PULSAR-ICI +/- IMSA101 in Patients with Oligoprogressive Solid Tumor Malignancies

Comprehensive Outcomes for After Cancer Health

Food Survey, Curbside, Remote APPs SCFI

SpineJack System Postmarket Registry

Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL)

A Phase III Trial of e-TNS for the Acute Treatment of Migraine

Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness