Clinical Trials in Tennessee

Showing 5821-5840 of 20,239 trials

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

NCT02437136

The purpose of this study is to determine the safety and tolerability of entinostat used in combination with pembrolizumab in participants with NSCLC. Additionally, the purpose of the study is to assess how effective entinostat and pembrolizumab are in combination in participants with NSCLC, Melanoma, and Mismatch-Repair Proficient CRC.

Non-Small Cell Lung CancerMelanomaMismatch Repair-Proficient Colorectal Cancer

Syndax Pharmaceuticals191 participantsStarted Aug 2015

New Haven, Connecticut, United States • Atlanta, Georgia, United States • Baltimore, Maryland, United States +8 more locations

COMPLETEDNA29 miles

Technology Based Sedentary Reduction Intervention in Patients With Type 2 Diabetes

NCT05691452

The purpose of this study is to develop and test an 8-week sedentary behavior reduction intervention ("Sit Less" program) for patients with type 2 diabetes. The program aims to reduce and break sitting times among this population using an objective activity monitor and mHealth. The investigators will test the program to help diabetes patients break up sitting time, reduce daily sitting time, and move more. The investigators will also study preliminary effects of the SB reduction intervention on light physical activity, cardiometabolic markers and patient-centered outcomes, and whether diabetes patients like the program and can follow it.

Type 2 DiabetesSedentary BehaviorPhysical Activity

Vanderbilt University31 participantsStarted Jan 2023

Nashville, Tennessee, United States

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

Technology Based Sedentary Reduction Intervention in Patients With Type 2 Diabetes

Find Trials by Condition in Tennessee

EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders

Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)

Study of ORIC-533 in Relapsed or Refractory Multiple Myeloma

Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai

LOVE Trial: Limits On Vaginal Intercourse After Mid-urEthral Sling

Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-3)

Aging Back Clinics

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Study to Compare 2 Botulinum Type A Toxins in the Treatment of Glabellar Frown Lines

A Study to Compare Efficacy, PK, PD, Safety and IMM of MB09 to Prolia® [EU-sourced] in Postmenopausal Osteoporosis.

A Study of JR-171 in Patients With Mucopolysaccharidosis I